Test Includes Amphetamine; barbiturate; benzodiazepines; cocaine; methadone; opiates; oxycodone/oxymorphone; phencyclidine (PCP); fentanyl; marijuana (THC) metabolite.

This test is a latex-enhanced, immunoassay that provides ultrasensitive detection and quantitation of free light chains (FLCs) in serum or urine earlier than electrophoresis. It is an aid in the diagnosis and treatment of multiple myeloma, lymphocytic neoplasms, Waldenstroms macroglobulinemia, and connective tissue diseases, such as systemic lup...

Preferred screening test for Cushing syndrome Diagnosis of pseudo-hyperaldosteronism due to excessive licorice consumption Test may not be useful in the evaluation of adrenal insufficiency

Monitoring tobacco use
 
Monitoring patients on nicotine-replacement therapy for concurrent use of tobacco products

Detect the presence of prescribed, over-the-counter, and illicit drugs for the purpose of medical drug monitoring.

Values above 10 mg/24 hours occur in carcinoid syndrome. Slight elevations also occur in nontropical sprue and after reserpine administration.

Detection and quantitation of BK Virus (BKV) in urine stabilized in cobas® PCR Media can be used as an aid in the diagnosis and management of BK virus infections.

Evaluate renal disease; monitor certain types of malignancies and AIDS  

Twenty-four hour urine collections  for oxalate are indicated in patients with surgical loss of distal small intestine, especially those with Crohn's disease. The incidence of nephrolithiasis in patients who have inflammatory bowel disease is 2.6% to 10%.1

Porphobilinogen levels in the urine should be measured during acute attacks of abdominal pain, extremity pain or paresthesias, tachycardia, nausea and vomiting, neurologic abnormalities, and to investigate characterized by urinary excretion of porphobilinogen and δ-aminolevulinic acid during acute attacks. Increased urinary excretion of por...

Evaluating patients with possible inborn errors of metabolism using random urine specimens May aid in evaluation of endocrine disorders, liver diseases, muscle diseases, neoplastic diseases, neurological disorders, nutritional disturbances, renal failure, and burns Includes quantitation of the following amino acids: phosphoserine, phosphoethanol...

Test Includes Coproporphyrins I and III; uroporphyrins; hepatocarboxylporphyrins; hexacarboxylporphyrins; pentacarboxylporphyrins Urine porphyrins are useful for the evaluation of cutaneous photosensitivity to exclude porphyria cutanea tarda (PCT). Evaluation of neurologic and/or psychiatric symptoms associated with acute porphyrias, such as ac...

Evaluate porphyrias, including those involving deficiencies of enzymes that are needed for heme synthesis and chemical porphyrias.

A timed 24-hour urine collection is the preferred specimen for measuring and interpreting this urinary analyte. Random collections normalized to urinary creatinine may be of some clinical use in patients who cannot collect a 24-hour specimen, typically small children.

Cystinuria is an autosomal recessive disease in which dibasic amino acids, including cystine, are excreted in excess. Cystine kidney stones account for approximately 1-3% of all kidney stones. Age of onset is often younger than with other types of kidney stones and the recurrence is approximately one-third.

Measure histamine that was released in vivo prior to collection of the specimen; evaluate possible systemic mastocytosis.

Homovanillic acid (HVA) measurement in urine is used for screening children for catecholamine-secreting tumors such as neuroblastoma, pheochromocytoma, and other neural crest tumors and monitoring those who have had treatment for these tumors. HVA measurement is also useful to diagnose children with disorders of catecholamine metabolism such as...

Urinary measurements are appropriate for assessing ongoing exposure to inorganic mercury.  

Arsenic is used in some pesticides and industrial applications.

Detect presence of flunitrazepam, a potent sedative-hypnotic with a reputation as a “date-rape” drug.

Detect MDMA (methylenedioxymethamphetamine) and related compounds in urine

Urinary lead concentrations may be used to monitor detoxification therapy.

Assessment of iodine toxicity or recent exposure in a 24-hour urine collection Monitoring iodine excretion rate as index of replacement therapy

Detect use of gabapentin, an anticonvulsant and neuromodulator

Detecting toxic thallium exposure in 24-hour urine specimens

Aid in evaluation of patient with allergic signs and symptoms, such as anaphylaxis. May assist when diagnosing and monitoring mast-cell activation disorders or when evaluating histamine production over a longer time frame.

Detect use of zolpidem, a non-benzodiazepine sedative/hypnotic

Intended for symptomatic patients, or patients with risk factors, suspected of urinary tract infection.

Determination of TPMT levels that may be associated with toxicity of anticancer and anti-inflammatory drugs

Detect Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma spp

Aiding in detecting  in urine from patients with disseminated histoplasmosis. 

Diagnose the presence of a pheochromocytoma, neuroblastoma, and ganglioneuroblastoma

Urine organic acid testing is useful in the diagnosis and monitoring of patients with inborn errors of organic acid metabolism, inborn errors of amino acid metabolism, urea cycle defects, and defects of the mitochondrial respiratory chain.

Monitor exposure to copper

Study of adrenocortical-renin-angiotensin system; adrenal cortical function test; evaluate renal hypertension; diagnose Conn syndrome (primary aldosteronism); evaluate hypokalemia with hypertension

Investigating suspected Cushing syndrome (hypercortisolism), when a 24-hour collection is prohibitive (ie, pediatric patients). Assisting in diagnosing acquired or inherited abnormalities of 11-beta-hydroxy steroid dehydrogenase (cortisol to cortisone ratio) Diagnosis of pseudohyperaldosteronism due to excessive licorice consumption This t...

Diagnose pheochromocytoma, VMA is of value for evaluation of hypertension, diagnose and follow up neuroblastoma, ganglioneuroma, and ganglioneuroblastoma. Most neuroblastoma patients excrete excess HVA in 24-hour collections. If VMA and HVA are both used in work-up, up to 80% of all cases will be detected.
 

Detecting arsenic, cadmium, mercury, and lead exposure and toxicity using 24-hour urine specimen

ALA is a precursor to uroporphyrin, coproporphyrin, and protoporphyrin. Concentrations of ALA are greatly increased in many patients with acute neurological forms of porphyrias and in some patients with chronic alcohol abuse.

Detect use of opiate and opioid class drugs Please note: this test includes both Buprenorphine(Suboxone) and Fentanyl

Monitoring of compliance utilizing tramadol Detection and confirmation of the illicit use of tramadol

Therapeutic drug management; detect presence of ketamine

This test is used to aid in the diagnosis and monitoring of patients with mucopolysacchariodoses (MPS) types I, II, III, IV, VI, and VII.

 This test is intended for use as an aid in diagnosing congenital CMV infection for neonates  under 21 days old. It is important to note that samples from patients aged 21 days and older should continue to be ordered through the existing test, Cytomegalovirus PCR Urine.

Assessing renal tubular injury or dysfunction using random urine collections Screening for other tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction

Testing performed at Northwell Rapid Response Laboratories

For use as an adjunct to culture for the presumptive diagnosis of past or current Legionella infection. This test only detects antigen from Legionella pneumophila serogroup 1. For culture, order "Legionella Culture" on a lower respiratory specimen.

Evaluation of osteoporosis and assessment of antiresorptive therapy

This test is intended for the in vitro qualitative detection of cytomegalovirus (CMV) DNA from urine . Results of this assay should be used in conjunction with the results of other clinical findings as an aid in the diagnosis of congenital CMV infection.

Confirming the presence of a myopathy associated with any 1 of the following disorders
-Hereditary myoglobinuria
-Phosphorylase deficiency
-Sporadic myoglobinuria
-Exertional myoglobinuria in untrained individuals
-Crush syndrome
-Myocardial infarction
-Myoglobinuria of progressive muscle disease
-Heat injury
...

Evaluating patients suspected of having systemic mastocytosis Identification of aspirin sensitivity in patient respiratory diagnoses

Clinically, the measurement ofcirculating catecholamines is valuable in the diagnosis of catecholamine secreting tumors associated chiefly with hypertension (pheochromocytomas, neuroblastomas, and gangliomas) and with the evaluation of orthostatic hypotension.

Screening for mast cell activation disorders including systemic mastocytosis using random urine specimens 2,3-Dinor-11beta-prostaglandin F2 alpha (2,3 BPG) is the most abundant metabolic product of prostaglandins released by activated mast cells. Systemic mastocytosis (SM) is a disease in which clonally derived mast cells accumulate in peripher...

Preferred screening test for detection of arsenic, cadmium, mercury, and lead in random urine specimens If the total arsenic concentration is 10 mcg/L or greater, then speciation will be performed at an additional charge.

Pediatric testing for the evaluation of hypertension; diagnose and follow up neuroblastoma, ganglioneuroma, and ganglioneuroblastoma. Most neuroblastoma patients excrete excess HVA in 24-hour collections. If VMA and HVA are both used in work-up, up to 80% of all cases will be detected.

Available for Hospital ED only

Screening for mast cell activation disorders including systemic mastocytosis using 24-hour urine specimens 2,3-Dinor-11beta-prostaglandin F2 alpha (2,3 BPG) is elevated in the urine of patients with systemic mastocytosis (SM). This test should be used as a screening test for SM. When 2,3 BPG is used in combination with urinary leukotriene E4 ...

The mean urinary citrate excretion rate in patients with idiopathic calcium urolithiasis has been found to be significantly lower than that of control groups. Hypocitraturia is common in patients with urolithiasis resulting from renal tubular acidosis and in patients with enteric hyperoxaluria. Citrate excretion is low in renal insufficiency.

Detection of oxycodone and/or oxymorphone

Cystinuria is an autosomal recessive disease in which dibasic amino acids, including cystine, are excreted in excess.

Vanillylmandelic acid (VMA) is the major urinary product resulting from the metabolic degradation of catecholamine, norepinephrine and epinephrine. Elevated concentrations of VMA are commonly found in cases of catecholamine secreting tumors such as pheochromocytoma, neuroblastoma, and ganglioneuroma.

Urinary measurements are appropriate for assessing ongoing exposure to inorganic mercury.

Aiding in the evaluation of patients at-risk for mast cell activation syndrome (eg, systemic mastocytosis, IgE-mediated allergies, or aspirin-exacerbated respiratory disease) using 24-hour urine collections

Use to detect hemosiderinuria secondary to excess hemolysis.

Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis

Detect presence of the kratom alkaloid mitragynine, a mood altering opioid receptor agonist, which has both stimulant and opioid effects.

Panel includes: amphetamines, barbiturate, benzodiazepines, cocaine metabolites, methadone, opiates, and fentanyl

Zinc measurements are used to detect and monitor industrial, dietary, and accidental exposure to zinc. Also, zinc measurements may be used to evaluate health and monitor response to treatment.

Intended for the qualitative detection of S. pneumoniae and L. pneumophila (primarily serogroup 1) antigens in human urine samples

An important test for identifying early kidney disease in patients with diabetes or other risk factors (eg, hypertension).

This test is intended to aid in the diagnosis of both pneumococcal meningitis and pneumococcal pneumonia in conjunction with culture. This test should not be used as a test of cure. The clinical utility of this test in pediatric patients has not been determined.