24 Hour Urine, 2,3-Dinor 11 Beta-Prostaglandin F2 Alpha

Synonyms

• LAB1075
• PGE2
• PROSTAGLANDIN E2, URINE

Cerner Name

2,3-dinor 11B-Prostaglandin F2a, 24U

Clinical Info

Screening for mast cell activation disorders including systemic mastocytosis using 24-hour urine specimens
2,3-Dinor-11beta-prostaglandin F2 alpha (2,3 BPG) is elevated in the urine of patients with systemic mastocytosis (SM).
This test should be used as a screening test for SM.
When 2,3 BPG is used in combination with urinary leukotriene E4 and N-methyl histamine, the sensitivity for SM detection increases to 90%.

Specimen Sources

Urine, Catheter Urine, Clean Catch

Specimen Types

Urine

Container

24hr Ur No Preserv

Collection Instructions

Container/Tube: 24 Hr Urine container. No preservative
Specimen : 5 mL (4 mL min)
Transport Temperature: Refrigerated
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen during collection, and send specimen refrigerated.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Patient Preparation: Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAID) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen.

Specimen Volume

5 mL (4 mL min)

Transport Instructions

Refrigerated

Specimen Stability

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Enzymatic Colorimetric Assay

Days Performed

Monday, Thursday

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT

84150
82570

PDM

1759101

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms