Random Urine, Vanillylmandelic Acid (VMA) and Homovanillic Acid (HVA) Build info

Synonyms

• RANDOM URINE, VANILLYLMANDELIC ACID (VMA) AND HOMOVANILLIC ACID (HVA)
• VMAHVA
• VMA AND HVA, CHILD
• LAB11061

Short Name

VMA AND HVA, CHILD

Procedure Master Number

LAB11061

Procedure ID

114524

Clinical Info

First preferred test for screening for catecholamine-secreting tumors in a random urine specimen when requesting both homovanillic acid and vanillylmandelic acid
Supporting a diagnosis of neuroblastoma
Monitoring patients with a treated neuroblastoma

Specimen Type

Urine

Container

Urine Cntr

Collection Instructions

Container/Tube: Sterile cup
Volume: 5 mL random urine (2 mL min)
Collection Instructions:
1. Collect a random urine specimen.
2. Adjust urine pH to 1 to 5 with 50% acetic or hydrochloric
acid.
Patient Preparation: Administration of L-dopa may falsely
increase homovanillic acid and vanillylmandelic acid results; it
should be discontinued 24 hours prior to and during collection of
specimen.

Transport Instructions

Refrigerated

Specimen Stability

28 days Refrigerated
180 Days Frozen

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

TAT: 4-6 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

83150-HVA
84585-VMA
LOINC Code: 90250-2

PDM

5908565

Results