24 Hour Urine, N-Methylhistamine

Synonyms

• LAB11043
• N-METHYLHISTAMINE, 24HR UR
• N-METHYLHISTAMINE, 24HR URINE
• NMETHHIS24

Cerner Name

N-Methylhistamine, 24hr UR

Clinical Info

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using 24-hour urine collection specimens
Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis

Specimen Sources

Bladder Kidney, Left Kidney, Right Ureter, Left Ureter, Right Urine, Catheter Urine, Clean Catch

Specimen Types

Urine

Specimen Volume

5 mL from well mixed 24 Hr urine collection (3 mL min)

Container

24hr Ur No Preserv

Collection Instructions

Container/Tube: 24 Hr urine container No preservative
Specimen: 5 mL from well mixed 24 Hr urine collection (3 mL min)
Transport Temperature: Refrigerated
Stability: 14 Days Room Temperature
28 Days Refrigerated or Frozen
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these
medications increase N-methylhistamine (NMH) levels.

Transport Instructions

Refrigerated

Specimen Stability

14 Days Room Temperature
28 Days Refrigerated or Frozen
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as
these medications increase N-methylhistamine (NMH) levels.

Methodology

N-methylhistamine: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Creatinine 24: Enzymatic Colorimetric Assay

Days Performed

TAT; 4-8 Days

Performing Laboratories

Mayo Medical Laboratories

CPT

82542
LOINC Code: 44340-8

PDM

1859099

Results

Result Interpretation

Forms