Inpatient and Outpatient Orderable

24 Hour Urine, N-Methylhistamine

Synonyms

  • LAB11043
  • N-METHYLHISTAMINE, 24HR UR
  • N-METHYLHISTAMINE, 24HR URINE
  • NMETHHIS24

Cerner Name

N-Methylhistamine, 24hr UR

Clinical Info

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using 24-hour urine collection specimens
Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis

Specimen Sources

Bladder Kidney, Left Kidney, Right Ureter, Left Ureter, Right Urine, Catheter Urine, Clean Catch

Specimen Types

Urine

Container

24hr Ur No Preserv

Collection Instructions

Container/Tube: 24 Hr urine container No preservative
Specimen: 5 mL from well mixed 24 Hr urine collection (3 mL min)
Transport Temperature: Refrigerated
Stability: 14 Days Room Temperature
28 Days Refrigerated or Frozen
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these
medications increase N-methylhistamine (NMH) levels.

Specimen Volume

5 mL from well mixed 24 Hr urine collection (3 mL min)

Transport Instructions

Refrigerated

Specimen Stability

14 Days Room Temperature
28 Days Refrigerated or Frozen
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as
these medications increase N-methylhistamine (NMH) levels.

Methodology

N-methylhistamine: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Creatinine 24: Enzymatic Colorimetric Assay

Days Performed

TAT; 4-8 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

82542
LOINC Code: 44340-8

PDM

1859099

Only Orderable at Locations:

Orderable Everywhere

Results
Component Name Base Name Common Name External Name
N-METHYLHISTAMINE, U NMETHYLHIST N METHYLHISTAMINE, U N-Methylhistamine, 24 Hr, U
COLLECTION DURATION COLLDUR COLLECTION DURATION Collection Duration
URINE VOLUME URINEVOLUME URINE VOLUME Urine Volume
CREATININE CONC CREATCONC CREATININE CONC Creatinine Concentration, 24 HR, U
CREATININE, 24 HOUR URINE CREAT24HRUR CREATININE 24H UR Creatinine, 24H Ur

Result Interpretation

N-METHYLHISTAMINE

0-5 years: 120-510 mcg/g creatinine

6-16 years: 70-330 mcg/g creatinine

>16 years: 30-200 mcg/g creatinine

    CREATININE

Males: 930-2955 mg/24 hours

Females: 603-1783 mg/24 hours

 

Reference values have not been established for patients who are younger than 18 years of age.

Forms
LAB11043 build edit