24 Hour Urine, N-Methylhistamine

Synonyms

  • LAB11043
  • N-METHYLHISTAMINE, 24HR UR
  • N-METHYLHISTAMINE, 24HR URINE
  • NMETHHIS24

Cerner Name

N-Methylhistamine, 24hr UR

Clinical Info

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using 24-hour urine collection specimens
Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis

Specimen Sources

Bladder Kidney, Left Kidney, Right Ureter, Left Ureter, Right Urine, Catheter Urine, Clean Catch

Specimen Types

Urine

Specimen Volume

5 mL from well mixed 24 Hr urine collection (3 mL min)

Container

24hr Ur No Preserv

Collection Instructions

Container/Tube: 24 Hr urine container No preservative
Specimen: 5 mL from well mixed 24 Hr urine collection (3 mL min)
Transport Temperature: Refrigerated
Stability: 14 Days Room Temperature
28 Days Refrigerated or Frozen
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as these
medications increase N-methylhistamine (NMH) levels.

Transport Instructions

Refrigerated

Specimen Stability

14 Days Room Temperature
28 Days Refrigerated or Frozen
Patient Preparation: Patient must not be taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine as
these medications increase N-methylhistamine (NMH) levels.

Methodology

N-methylhistamine: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Creatinine 24: Enzymatic Colorimetric Assay

Days Performed

TAT; 4-8 Days

Performing Laboratories

Mayo Medical Laboratories

CPT

82542
LOINC Code: 44340-8

PDM

1859099

Results
Component Name Base Name Common Name External Name
N-METHYLHISTAMINE, U NMETHYLHIST N METHYLHISTAMINE, U N-Methylhistamine, 24 Hr, U
COLLECTION DURATION COLLDUR COLLECTION DURATION Collection Duration
URINE VOLUME URINEVOLUME URINE VOLUME Urine Volume
CREATININE CONC CREATCONC CREATININE CONC Creatinine Concentration, 24 HR, U
CREATININE, 24 HOUR URINE CREAT24HRUR CREATININE 24H UR Creatinine, 24H Ur

Result Interpretation

N-METHYLHISTAMINE

0-5 years: 120-510 mcg/g creatinine

6-16 years: 70-330 mcg/g creatinine

>16 years: 30-200 mcg/g creatinine

    CREATININE

Males: 930-2955 mg/24 hours

Females: 603-1783 mg/24 hours

 

Reference values have not been established for patients who are younger than 18 years of age.

Forms
Immunology LAB11043 build edit