CSF, Oligoclonal Bands

Synonyms

• LAB740
• MS PANEL
• MULTIPLE SCLEROSIS
• OLIGOCLONAL BANDING

Cerner Name

Oligoclonal Banding

Clinical Info

Oligoclonal Bands (IgG), CSF - Oligoclonal bands are present in the CSF of more than 85% of patients with clinically definite multiple sclerosis (MS). To distinguish between oligoclonal bands in the CSF due to a peripheral gammopathy and oligoclonal bands due to local production in the CNS, serum and CSF should be tested simultaneously. Oligoclonal bands can however be observed in a variety of other diseases, e.g., subacute sclerosing panencephalitis, inflammatory polyneuropathy, CNS lupus, and brain tumors and infarctions.
Serum and spinal fluid are required for this test

Specimen Sources

CSF Reservoir Lumbar Puncture VP Shunt Aspirate

Specimen Types

Cerebrospinal Fluid

Container

Gold-top tube(s) or plain, red-top tube(s) AND CSF Tube

Collection Instructions

Serum and spinal fluid are required for this test.

Serum
Container/Tube: Gold-top tube(s) or plain, red-top tube(s)
Specimen: 1 mL of serum (0.5 mL min)
Transport Temperature: Refrigerate
Collection Instructions:
Note: Indicate serum on request form.
2. Label specimen appropriately (serum).

Spinal Fluid
Container/Tube: Screw-capped, sterile vial
Specimen: 1 mL of spinal fluid (0.5 mL min)
Transport Temperature: Refrigerated. Maintain sterility and forward promptly.

Note: Label specimen appropriately (spinal fluid/ Serum).

Specimen Volume

0.5 mL of serum

Transport Instructions

Refrigerate

Specimen Stability

8 Hours Room Temperature
5 Days Refrigerated
14 Days Frozen

Methodology

Isoelectric focusing(IEF)

Days Performed

TAT: 5-7 Days

Performing Laboratory

Quest Diagnostics Nichols Institute,

CPT

83916
LOINC Code: 12782-9

PDM

5300847

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms

• Protein Elect CSF-interp-reflx (CSFPE) Protein Elect CSF Serum Part (CSFPE2) Discontinued Test 11-21
• Oligoclonal Banding Test Update (OLIGO) 3-14-2022