AChE, Amniotic Fluid With Reflex to Fetal Hemoglobin AChE AF

Synonyms

Allscripts (AEHR) Order Name

AChE, Amniotic Fluid With Reflex to Fetal Hemoglobin

Sunrise Clinical Manager (SCM) Order Name

AChE, Amniotic Fluid With Reflex to Fetal Hemog

EPIC Order Name

Acetylcholinesterase

Clinical Info

Analysis of midtrimester amniotic fluid for detection of open neural tube defects and ventral wall defects
Test Includes
Detection of AChE. The reflex to fetal hemoglobin (Hb F) will be performed,
if necessary, to ascertain false elevations of amniotic fluid AFP.

Specimen Type

Body Fluid

Specimen Volume

Container

Sterile

Collection Instructions

Container/Tube: Sterile Plastic container or vial. Do not use urine containers or tubes with rubber
stoppers. Rubber is toxic to amniocytes.
Specimen 3 mL Amniotic Fluid
Transport Temperature: Room Temperature
Specimen Stability: Room Temperature 6 days
Patient Preparation
The patient should have undergone ultrasound studies to verify fetal viability,
detect multiple gestation, confirm gestational age, localize placenta, and
detect fetal and uterine pathology.
Collection
Avoid contamination of amniotic fluid with maternal or fetal blood. As little
as one drop of fetal blood can cause false-positive results during assay of
amniotic fluid. Amniotic fluid should be collected by the attending physician.

Transport Instructions

Specimen Stability

Amniotic fluid supernatant samples are stable at ambient temperature for 6 days.

Additional Information:
1. Indications for Testing: Suspicion of Open neural tube defect due to elevated
Amniotic Fluid AFP or ultrasound findings.

Methodology

Acrylamide gel electrophoresis; isoelectric focusing (IEF)

Days Performed

TAT: 5-13 Days

Performing Laboratory

LabCorp

CPT

82013

PDM

225101

Result Interpretation

Negative

Forms

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