Acetylcholinesterase

Synonyms

• ACETYLCHOLINESTERASE, AMNIOTIC FLUID
• ACHE
• AChE, Amniotic Fluid With Reflex to Fetal Hemog
• AChE, Amniotic Fluid With Reflex to Fetal Hemoglobin
• AMNIOTIC FLUID
• LAB428

Cerner Name

AChE, Amniotic Fluid With Reflex to Fetal Hemoglobin

Clinical Info

Analysis of midtrimester amniotic fluid for detection of open neural tube defects and ventral wall defects
Test Includes
Detection of AChE. The reflex to fetal hemoglobin (Hb F) will be performed,
if necessary, to ascertain false elevations of amniotic fluid AFP.

Specimen Sources

Amniotic Sac

Specimen Types

Amniotic Fluid

Specimen Volume

Container

Sterile

Collection Instructions

Container/Tube: Sterile Plastic container or vial. Do not use urine containers or tubes with rubber
stoppers. Rubber is toxic to amniocytes.
Specimen 3 mL Amniotic Fluid
Transport Temperature: Room Temperature
Specimen Stability: Room Temperature 6 days
Patient Preparation
The patient should have undergone ultrasound studies to verify fetal viability,
detect multiple gestation, confirm gestational age, localize placenta, and
detect fetal and uterine pathology.
Collection
Avoid contamination of amniotic fluid with maternal or fetal blood. As little
as one drop of fetal blood can cause false-positive results during assay of
amniotic fluid. Amniotic fluid should be collected by the attending physician.

Transport Instructions

Specimen Stability

Amniotic fluid supernatant samples are stable at ambient temperature for 6 days.

Additional Information:
1. Indications for Testing: Suspicion of Open neural tube defect due to elevated
Amniotic Fluid AFP or ultrasound findings.

Methodology

Acrylamide gel electrophoresis; isoelectric focusing (IEF)

Days Performed

TAT: 5-13 Days

Performing Laboratory

LabCorp

CPT

82013

PDM

225101

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms

• Prenatal Cytogentics Requisiton