Nicotine and Metabolite NICO

Synonyms

Allscripts (AEHR) Order Name

Nicotine and Metabolite, Serum

Sunrise Clinical Manager (SCM) Order Name

Nicotine and Metabolite, Serum

EPIC Order Name

Nicotine and Metabolite, Serum

Clinical Info

This assay is used for the detection of nicotine and cotinine in serum and plasma to determine the tobacco exposure status of the individual. Nicotine has a short half-life of approximately forty minutes; its presence may indicate recent tobacco exposure. Cotinine, the major nicotine metabolite, has a half-life of 24 hours and is detectable for several days after cessation of tobacco exposure.

Specimen Type

Blood

Container

Red Top Tube

Collection Instructions

Container/Tube: Red top
Specimen : 1.0 mL serum (0.5 mL min)

Transport Instructions

Refrigerated

Specimen Stability

3 Days Room Temperature     
21 Days Refrigerated
30 Days Frozen

Methodology

Chromatography/Mass Spectrometry

Days Performed

TAT: 3-4 Days Days

Performing Laboratory

Quest Diagnostics 

CPT

80323 

PDM

5908600

Result Interpretation

Nicotine, Serum/Plasma

Smoker 2-10 ng/mL
Nonsmoker ≤4 ng/mL


Cotinine, Serum/Plasma

Smoker 16-145 ng/mL
Nonsmoker ≤8 ng/mL

Forms


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