Neuron Specific Enolase, CSF NSECSF

Synonyms

Allscripts (AEHR) Order Name

Neuron Specific Enolase, CSF

Sunrise Clinical Manager (SCM) Order Name

Neuron Specific Enolase, CSF

EPIC Order Name

CSF, Neuron-specific Enolase (NSE)

Clinical Info

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease

Specimen Type

CSF

Specimen Volume

0.5 mL CSF (0.3 mL min0

Container

Sterile

Collection Instructions

Container/Tube: Sterile CSF vial
Specimen: 0.5 mL CSF (0.3 mL min0
Transport Temperature: Refrigerated
Stability: 72 Hours Room Temperature
15 Days Refrigerated

Transport Instructions

Refrigerated

Specimen Stability

72 Hours Room Temperature
15 Days Refrigerated

Methodology

Homogeneous Time-Resolved Fluorescence
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Days Performed

TAT: 2- 4 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

83520
LOINC Code: 44802-7

PDM

215267

Result Interpretation

Normal:< or =15ng/mL
Indeterminate:15-30ng/mL
Elevated:>30ng/mL
Elevated results may indicate the need for additional workup. Possible causes may be NSE-secreting central nervous system/leptomeningeal tumor or rapid neuronal destruction from a variety of causes. In the context of dementia, elevated results may be suggestive of Creutzfeldt-Jakob disease.

Forms

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