Neuron Specific Enolase, CSF NSECSF

Synonyms

Allscripts (AEHR) Order Name

Neuron Specific Enolase, CSF

Sunrise Clinical Manager (SCM) Order Name

Neuron Specific Enolase, CSF

EPIC Order Name

CSF, Neuron Specific Enolase

Clinical Info

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease

Specimen Type

CSF

Container

Sterile

Collection Instructions

Container/Tube: Sterile CSF vial
Specimen: 0.5 mL CSF (0.3 mL min0
Transport Temperature: Refrigerated
Stability: 72 Hours Room Temperature
15 Days Refrigerated

Transport Instructions

Refrigerated

Specimen Stability

72 Hours Room Temperature
15 Days Refrigerated

Methodology

Homogeneous Time-Resolved Fluorescence
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Days Performed

TAT: 2- 4 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

83520
LOINC Code: 44802-7

PDM

215267

Result Interpretation

Normal:< or =15ng/mL
Indeterminate:15-30ng/mL
Elevated:>30ng/mL
Elevated results may indicate the need for additional workup. Possible causes may be NSE-secreting central nervous system/leptomeningeal tumor or rapid neuronal destruction from a variety of causes. In the context of dementia, elevated results may be suggestive of Creutzfeldt-Jakob disease.

Forms

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