CSF, Neuron-specific Enolase (NSE) Build info

Synonyms

• CSF, NEURON-SPECIFIC ENOLASE (NSE)
• NEURON SPECIFIC ENOLASE, CSF
• NSECSF
• NSE, CSF
• LAB11528

Procedure Name

CSF, NEURON-SPECIFIC ENOLASE (NSE)

Procedure Master Number

LAB11528

Procedure ID

115373

Clinical Info

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease

Specimen Sources

Specimen Types

Container

Sterile

Collection Instructions

Container/Tube: Sterile CSF vial
Specimen: 0.5 mL CSF (0.3 mL min0
Transport Temperature: Refrigerated
Stability: 72 Hours Room Temperature
15 Days Refrigerated

Specimen Volume

0.5 mL CSF (0.3 mL min0

Transport Instructions

Refrigerated

Specimen Stability

72 Hours Room Temperature
15 Days Refrigerated

Methodology

Homogeneous Time-Resolved Fluorescence
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Days Performed

TAT: 2- 4 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

83520
LOINC Code: 44802-7

PDM

Only Orderable at Locations:

Results

Result Interpretation

Normal:	< or =15	ng/mL
Indeterminate:	15-30	ng/mL
Elevated:	>30	ng/mL

Elevated results may indicate the need for additional workup. Possible causes may be NSE-secreting central nervous system/leptomeningeal tumor or rapid neuronal destruction from a variety of causes. In the context of dementia, elevated results may be suggestive of Creutzfeldt-Jakob disease.

Forms