Hepatitis C AB HEPC

Synonyms

Allscripts (AEHR) Order Name

Hepatitis C Ab w/reflex to qualitative HCVRNA

Sunrise Clinical Manager (SCM) Order Name

Hepatitis C Antibody Test

EPIC Order Name

Hepatitis C Virus (HCV) Antibody with Reflex to Qualitative Molecular Detection

Clinical Info

This is a testing algorithm for the diagnosis of HCV infection. Positive antibody results will reflex to confirmation by molecular detection.

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold-top tube(s)
1.0 mL serum
Allow 30 minutes to clot after collection
Transport Temperature: Refrigerate

Transport Instructions

Refrigerate

Specimen Stability

Core Laboratory
3 Days Room Temperature
7 Days Refrigerated
NSUH
3 Days Room Temperature
21 days refrigerated
3 months frozen -15 to -25C

Methodology

Chemiluminescent Microparticle Immunoassay (CMIA) - Northwell Core Labs - Outpatient
Electrochemiluminescence Immunoassay (ECLIA) - North Shore University Hosptal - Inpatient

Days Performed

Monday through Saturday

Performing Laboratory

Northwell Health Laboratories

CPT

86803

PDM

5302685

Result Interpretation

Northwell Core Laboratory (Outpatients)

S/CO Ratio                       Interpretation

0.00 – 0.79                         Non-Reactive

0.80 – 0.99                         Equivocal

> 1.00                                Reactive

Non-Reactive: Antibodies to HCV were not detected; does not exclude the possibility of recent exposure to HCV. No further action is needed unless recent infection is expected.

Equivocal: Antibodies to HCV may or may not be present. HCV RNA testing will follow to identify current infection.

Reactive: Presumptive evidence of antibodies to HCV. HCV RNA testing will follow to identify current infection.

***

North Shore University Hospital (Inpatient)

Cutoff Index (COI)                      Interpretation

≤0.89                                                Non-Reactive

0.90 ≤ COI < 1.00                             Border

> 1.00                                               Reactive

Border results are retested in duplicate (2 of 3 results) to resolve final results.

Non-Reactive: Antibodies to HCV were not detected; does not exclude the possibility of recent exposure to HCV. No further action is needed unless recent infection is expected.
 
Reactive: Presumptive evidence of antibodies to HCV. HCV RNA testing will follow to identify current infection.
 
Note: HCV antibody testing is performed on the Roche e602 analyzer.
 

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