Hepatitis C Virus (HCV) Antibody with Reflex to Qualitative Molecular Detection

Northwell Core Laboratory (Outpatients)

S/CO Ratio                       Interpretation

0.00 – 0.79                         Non-Reactive

0.80 – 0.99                         Equivocal

> 1.00                                Reactive

Non-Reactive: Antibodies to HCV were not detected; does not exclude the possibility of recent exposure to HCV. No further action is needed unless recent infection is expected.

Equivocal: Antibodies to HCV may or may not be present. HCV RNA testing will follow to identify current infection.

Reactive: Presumptive evidence of antibodies to HCV. HCV RNA testing will follow to identify current infection.

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North Shore University Hospital (Inpatient)

Cutoff Index (COI)                      Interpretation

≤0.89                                                Non-Reactive

0.90 ≤ COI < 1.00                             Border

> 1.00                                               Reactive

Border results are retested in duplicate (2 of 3 results) to resolve final results.

Non-Reactive: Antibodies to HCV were not detected; does not exclude the possibility of recent exposure to HCV. No further action is needed unless recent infection is expected.
 
Reactive: Presumptive evidence of antibodies to HCV. HCV RNA testing will follow to identify current infection.
 
Note: HCV antibody testing is performed on the Roche e602 analyzer.