MTRX MTRX

Synonyms

Allscripts (AEHR) Order Name

Methotrexate Level, Serum

Sunrise Clinical Manager (SCM) Order Name

Methotrexate Level, Serum

EPIC Order Name

Methotrexate Level

Clinical Info

Specimens from patients who received glucarpidase as a high dose methotrexate rescue therapy should not be tested with this enzyme immunoassay to avoid the reporting of falsely elevated methotrexate values.

Specimen Type

Blood

Specimen Volume

1 mL of serum

Container

Red Top Tube

Collection Instructions

Specimens from patients who received glucarpidase as a high dose methotrexate rescue therapy should not be tested with this enzyme immunoassay to avoid the reporting of falsely elevated methotrexate values.

Transport Instructions

Refrigerate

Specimen Stability

2 weeks Refrigerated

Methodology

Enzyme Immunoassay

Days Performed

Monday through Sunday

Performing Laboratory

Northwell Core Lab at CFAM

CPT

80204

PDM

5900975

Result Interpretation

Methotrexate serum concentrations depend on indication for use, dosage, mode of administration, treatment regimen, individual pharmacokinetics, metabolism and other clinical factors.

Expected Methotrexate levels after high dose therapy
After 24 hours: approximately 10 mmol/L
After 48 hours: approximately 1 mmol/L
After 72 hours: approximately 0.2 mmol/L

Forms