Methotrexate Level

Synonyms

  • LAB481
  • METHOTREXATE LEVEL
  • METOJECT
  • MEXATE
  • MTX
  • NORDIMET
  • OTREXUP
  • RASUVO
  • REDITREX
  • TREXALL
  • XATMEP

Cerner Name

MTRX

Clinical Info

Specimens from patients who received glucarpidase as a high dose methotrexate rescue therapy should not be tested with this enzyme immunoassay to avoid the reporting of falsely elevated methotrexate values.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL of serum

Container

Red Top Tube

Collection Instructions

Specimens from patients who received glucarpidase as a high dose methotrexate rescue therapy should not be tested with this enzyme immunoassay to avoid the reporting of falsely elevated methotrexate values.

Transport Instructions

Refrigerate

Specimen Stability

2 weeks Refrigerated

Methodology

Enzyme Immunoassay

Days Performed

Monday through Sunday

Performing Laboratories
  • Core Lab Laboratory
  • LIJ Hospital Laboratory
  • Lenox Hill Laboratory
  • Northwell Health-CFAM

CPT

80204

PDM

5900975

Results
Component Name Base Name Common Name External Name
METHOTREXATE LEVEL, SERUM MTX METHOTREXATE LVL Methotrexate

Result Interpretation

Methotrexate serum concentrations depend on indication for use, dosage, mode of administration, treatment regimen, individual pharmacokinetics, metabolism and other clinical factors.

Expected Methotrexate levels after high dose therapy
After 24 hours: approximately 10 mmol/L
After 48 hours: approximately 1 mmol/L
After 72 hours: approximately 0.2 mmol/L

Forms
Tox/TDM LAB481 build edit