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Androstenedione
ANDSTEN
Synonyms
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Allscripts (AEHR) Order Name
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Androstenedione, Serum
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Sunrise Clinical Manager (SCM) Order Name
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Androstenedione, Serum
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EPIC Order Name
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Androstenedione
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Clinical Info
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Androstenedione (also known as 4-androstenedione and δ4-androstenedione) is a 19-carbon steroid hormone produced in the adrenal
glands and the gonads that is the common precursor in the biochemical pathway that produces the androgen testosterone and the
estrogens estrone and estradiol.1-7 Androstenedione has approximately one tenth of the androgenic potency of testosterone.
1 Androstenedione is synthesized by means of two biochemical pathways. The predominant pathway involves conversion of
17-hydroxypregnenolone to dehydroepiandrosterone (DHEA) catalyzed by the enzyme 17,20-lyase, with subsequent conversion
of DHEA to androstenedione catalyzed by the enzyme 3-β-hydroxysteroid dehydrogenase. A secondary pathway for androstenedione
production involves conversion of 17-hydroxyprogesterone to androstenedione directly by 17,20-lyase. 17,20-lyase is required for
both pathways of androstenedione synthesis.
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Specimen Type
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Blood
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Container
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Red Top Tube
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Collection Instructions
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Container/Tube: Red top tube (No gel tube)
Specimen : 1 mL serum (0.5 mL min)
Transport Temperature: Refrigerated
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Transport Instructions
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Refrigerated...
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Specimen Stability
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14 Days Room Temperature
14 Days Refrigerated
14 Days Frozen
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Methodology
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Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
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Days Performed
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TAT: 5-7 Days
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Performing Laboratory
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Laborp
This test was developed, and its performance characteristics determined, by LabCorp.
It has not been cleared or approved by the US Food and Drug Administration (FDA).
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CPT
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82157
LOINC Code 1854-9
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PDM
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5900260
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Result Interpretation
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Age
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Male (ng/dL)
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Female (ng/dL)
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0 to 30 d
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Not established
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Not established
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1 to 6 m
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0−50
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0−81
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7 m to 1 y
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0−41
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0−48
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2 to 5 y
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0−22
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0−67
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6 to 8 y
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10−78
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0−67
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9 to 14 y
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10−78
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28−288
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15 to 60 y
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27−152
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41−262
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61 to 80 y
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22−96
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17−99
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>80 y
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Not established
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Not established
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Forms
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