Androstenedione Build info

Synonyms

• ANDROSTENEDIONE
• ANDROGEN
• LAB518

Short Name

ANDROSTENEDI

Procedure Master Number

LAB518

Procedure ID

17731

Clinical Info

Androstenedione (also known as 4-androstenedione and δ4-androstenedione) is a 19-carbon steroid hormone produced in the adrenal
glands and the gonads that is the common precursor in the biochemical pathway that produces the androgen testosterone and the
estrogens estrone and estradiol.1-7 Androstenedione has approximately one tenth of the androgenic potency of testosterone.
1 Androstenedione is synthesized by means of two biochemical pathways. The predominant pathway involves conversion of
17-hydroxypregnenolone to dehydroepiandrosterone (DHEA) catalyzed by the enzyme 17,20-lyase, with subsequent conversion
of DHEA to androstenedione catalyzed by the enzyme 3-β-hydroxysteroid dehydrogenase. A secondary pathway for androstenedione
production involves conversion of 17-hydroxyprogesterone to androstenedione directly by 17,20-lyase. 17,20-lyase is required for
both pathways of androstenedione synthesis.

Specimen Sources

Specimen Types

Container

Red Top Tube

Collection Instructions

Container/Tube: Red top tube (No gel tube)
Specimen : 1 mL serum (0.5 mL min)
Transport Temperature: Refrigerated

Transport Instructions

Refrigerated...

Specimen Stability

14 Days Room Temperature
14 Days Refrigerated
14 Days Frozen

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

TAT: 5-7 Days

Performing Laboratory

Laborp
This test was developed, and its performance characteristics determined, by LabCorp.
It has not been cleared or approved by the US Food and Drug Administration (FDA).

CPT

82157
LOINC Code 1854-9

PDM

Only Orderable at Locations:

Results