Acetyl Choline Receptor AB ACRAB

Synonyms

Allscripts (AEHR) Order Name

Acetylcholine Receptor Binding Antibody

Sunrise Clinical Manager (SCM) Order Name

Acetylcholine Receptor Binding Antibody

EPIC Order Name

Acetylcholine Receptor (AChR)-binding Antibody

Clinical Info

This assay is the primary test for confirming the diagnosis of acquired myasthenia gravis.
 

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube:  Gold-top tube(s)
Specimen:  1 mL of serum(0.3 mL min)
                       No isotopes administered 24 hours prior to venipuncture
Transport Temperature:  Refrigerate
Stability:  14 days Room Temperature, Refrigerated, Frozen
Rejection: Gross hemolysis; gross icterus; gross lipemia
                

Transport Instructions

Refrigerate

Specimen Stability

14 days Room Temperature, Refrigerated, Frozen
Rejection: Gross hemolysis; gross icterus; gross lipemia
                

Methodology

This assay measures antibodies that precipitate solublized muscle AChR that has been complexed with radiolabeled alpha-bungarotoxin (?BTX). Antibodies that bind to the receptor regions that are not sterically blocked by the ?BTX are detected.

Days Performed

Performing Laboratory

LabCorp

CPT

83519
 
LOINC: 11034-6

PDM

5900210

Result Interpretation

Negative: 0.00−0.24 nmol/L
 Borderline: 0.25−0.40 nmol/L
 Positive: >0.40 nmol/L

Forms