Acetylcholine Receptor (AChR)-binding Antibody

Synonyms

  • ACETYLCHOLINE RECEPTOR (ACHR)-BINDING ANTIBODY
  • ACHR
  • LAB836

Cerner Name

Acetyl Choline Receptor AB

Clinical Info

This assay is the primary test for confirming the diagnosis of acquired myasthenia gravis.
 

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL of serum(0.3 mL min)

Container

Gold Top Tube

Collection Instructions

Container/Tube:  Gold-top tube(s)
Specimen:  1 mL of serum(0.3 mL min)
                       No isotopes administered 24 hours prior to venipuncture
Transport Temperature:  Refrigerate
Stability:  14 days Room Temperature, Refrigerated, Frozen
Rejection: Gross hemolysis; gross icterus; gross lipemia
                

Transport Instructions

Refrigerate

Specimen Stability

14 days Room Temperature, Refrigerated, Frozen
Rejection: Gross hemolysis; gross icterus; gross lipemia
                

Methodology

This assay measures antibodies that precipitate solublized muscle AChR that has been complexed with radiolabeled alpha-bungarotoxin (?BTX). Antibodies that bind to the receptor regions that are not sterically blocked by the ?BTX are detected.

Days Performed

Performing Laboratories

LabCorp

CPT

86041

PDM

5900210

Results
Component Name Base Name Common Name External Name
ACRM BINDING ANTIBODY ACRMBIND ACRMBINDING AB AChR Binding Ab

Result Interpretation

Negative: 0.00−0.24 nmol/L
 Borderline: 0.25−0.40 nmol/L
 Positive: >0.40 nmol/L

Forms
Chemistry LAB836 build edit