Phosphatidyl Serine Antibodies PSAB

Synonyms
Allscripts (AEHR) Order Name	Phosphalidylserine Antibodies
Sunrise Clinical Manager (SCM) Order Name	Phosphatidylserine Antibodies
EPIC Order Name	Phosphatidylserine Antibodies (IgA, IgG, IgM)
Clinical Info	Not a recommended panel for the diagnosis of antiphospholipid syndrome (APS). The combined IgG and IgM Phosphatidylserine test is the preferred second-line testing in seronegative APS.
Specimen Type	Blood
Specimen Volume	0.5 mL serum (Min: 0.25 mL)
Container	Gold Top Tube
Collection Instructions	Container/Tube: Gold-top tube Specimen: 0.5 mL serum (Min: 0.25 mL) Transport Temperature: Refrigerate
Transport Instructions	Refrigerate
Specimen Stability	Room Temperature: 2 Days Refrigerated: 2 weeks Frozen: 1 month
Methodology	Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Days Performed	TAT: 2-7 Days
Performing Laboratories	ARUP Laboratory
CPT	86148 x 3
PDM	5909092
Result Interpretation Interpretive Data IgG and/or IgM antibodies to phosphatidylserine (aPS) may be associated with a positive test for anti-cardiolipin autoantibodies (aCL) and risk for obstetric antiphospholipid syndrome (APS). Strong clinical correlation is recommended in the absence of lupus anticoagulant, IgG and/or IgM cardiolipin and/or beta2 glycoprotein antibodies. Isolated presence of IgM or IgG antibodies to aPS may have questionable clinical significance for APS and/or SLE. If results are positive, repeat testing with two or more specimens drawn at least 12 weeks apart to demonstrate persistence of antibodies. Results should not be used alone for diagnosis and must be interpreted in light of APS-specific clinical manifestations and/or other criteria phospholipid antibody tests.
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