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Fibrin Split Products
FIB SPLIT
Synonyms
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Allscripts (AEHR) Order Name
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Fibrin Split Products
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Sunrise Clinical Manager (SCM) Order Name
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Fibrin Split Products
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EPIC Order Name
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Fibrin Split Products
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Clinical Info
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Specimen Type
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Blood
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Container
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Blue Top Tube
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Collection Instructions
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Container/Tube: Light blue-top (3.2% sodium citrate) tube
Specimen: 0.5 mL citrated plasma
Transport Temperature: Frozen
Collection Instruction:
1. If no other tube is drawn, draw a discard tube.
2. If there is a delay in transport, spin down, spin plasma again, and send citrate platelet-poor plasma. Double-centrifuged specimens are critical for accurate results as platelet contamination may cause spurious results.
3. Fill tube completely.
4. Mix by gently inverting several times.
5. Send aliquot frozen.
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Transport Instructions
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Frozen
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Specimen Stability
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Methodology
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Latex Agglutination/Manual (semi-quantitative)
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Days Performed
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Monday through Friday
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Performing Laboratory
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Northwell Health Laboratories
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CPT
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85362
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PDM
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5500593
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Result Interpretation
<5 µg/mL
Interpretation:
Under normal conditions, the fibrinolytic process is localized
on the fibrin clots because alpha2-antiplasmin and the plasminogen
activator inhibitors prevent fibrinolysis from spreading. During
disseminated intravascular coagulation (DIC), fibrinolysis spreads
and becomes systemic, in which case the degradation of circulating
fibrinogen will occur. Fragments that occur are very heterogeneous:
products derived from fibrin, soluble completes, degradation
products from fibrinogen, and from nonstabilized fibrin. An
abnormal fibrinolytic and/or fibrinogenolytic activity shown by
high levels of FDP in plasma can also be found in clinical states,
such as eclampsia, carcinoma (promyelocytic leukemia),
postoperative complications, cardiac and renal disorders, hepatic
disorders, fibrinolysis, pulmonary embolism, and deep vein
thrombosis (DVT). Positive result indicates the presence of FDP at
a concentration ≥2.5 mg/mL. This test should not be used to
rule out venous thromboembolism.
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Forms
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