Inpatient and Outpatient Orderable

Fibrin Split Products

Synonyms

  • DIC
  • FIBRIN SPLIT PRODUCTS
  • FIBRINOLYSIS
  • FSP
  • LAB761

Cerner Name

Fibrin Split Products

Clinical Info

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

Blue Top Tube

Collection Instructions

Container/Tube: Light blue-top (3.2% sodium citrate) tube
Specimen: 0.5 mL citrated plasma
Transport Temperature: Frozen
Collection Instruction:
1. If no other tube is drawn, draw a discard tube.
2. If there is a delay in transport, spin down, spin plasma again, and send citrate platelet-poor plasma. Double-centrifuged specimens are critical for accurate results as platelet contamination may cause spurious results.
3. Fill tube completely.
4. Mix by gently inverting several times.
5. Send aliquot frozen.

Specimen Volume

0.5 mL citrated plasma

Transport Instructions

Frozen

Specimen Stability

Methodology

Latex Agglutination/Manual (semi-quantitative)

Days Performed

Monday through Friday

Performing Laboratory

Northwell Health Laboratories

CPT

85362

PDM

5500593

Only Orderable at Locations:

Orderable Everywhere

Results
Component Name Base Name Common Name External Name
FIBRIN SPLIT PRODUCTS FIBRINSPLPRO FIBRIN SPLIT PRODUCTS Fibrin Split Products

Result Interpretation

<5 µg/mL
Interpretation:
Under normal conditions, the fibrinolytic process is localized on the fibrin clots because alpha2-antiplasmin and the plasminogen activator inhibitors prevent fibrinolysis from spreading. During disseminated intravascular coagulation (DIC), fibrinolysis spreads and becomes systemic, in which case the degradation of circulating fibrinogen will occur. Fragments that occur are very heterogeneous: products derived from fibrin, soluble completes, degradation products from fibrinogen, and from nonstabilized fibrin. An abnormal fibrinolytic and/or fibrinogenolytic activity shown by high levels of FDP in plasma can also be found in clinical states, such as eclampsia, carcinoma (promyelocytic leukemia), postoperative complications, cardiac and renal disorders, hepatic disorders, fibrinolysis, pulmonary embolism, and deep vein thrombosis (DVT). Positive result indicates the presence of FDP at a concentration ≥2.5 mg/mL. This test should not be used to rule out venous thromboembolism.

Forms
LAB761 build edit