Thyroglobulin and Thyroglobulin Antibody TYGL

Synonyms

TG

Allscripts (AEHR) Order Name

Thyroglobulin

Sunrise Clinical Manager (SCM) Order Name

Thyroglobulin Antibody

EPIC Order Name

Thyroglobulin and Thyroglobulin Antibody

Clinical Info


Test includes Thyroglobulin (Tg) and Thyroglobulin Antibody (anti-Tg).
Measurement of thyroglobulin concentration is recommended for monitoring of persistence or recurrence/metastatic disease in patients with differentiated thyroid cancer after total thyroidectomy (with or without radioiodine ablative therapy).

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold-top tube(s)
Specimen: 2 mL (1 mL min) of serum

Transport Instructions

Refrigerate

Specimen Stability

For Thyroglobulin 
14 days at 2-8 °C
24 months at -20 °C (± 5 °C). Freeze only once.
For Thyroglobulin Antibody
4 days at 2-8 °C
2 months at -20 °C (± 5 °C). Freeze only once

Methodology

Electrochemiluminescence Immunoassay
 

Days Performed

TAT: 2-4 Days

Performing Laboratory

Northwell Core Lab at CFAM

CPT

84432 - thyroglobulin
86800 - thyroglobulin antibody

PDM

5900117

Result Interpretation

This result was obtained using the Roche ELECSYS electrochemiluminescence assay. Results obtained using different assay methods cannot be directly compared due to differences in immunoassay design and antibody epitope recognition.

Note: The presence of thyroglobulin autoantibodies can interfere with the measurement of serum thyroglobulin.

 

American Thyroid Association Therapy Response Classification Threshold Values Among Patients With DTC

Excellent Response = Suppressed Tg < 0.2 ng/mL

Indeterminate Response = Suppressed Tg 0.2 to < 1.0 ng/mL

Biochemical Incomplete Response = Suppressed Tg ≥ 1.0 ng/mL

Reference: Thyroid 26.1 (2016): 1-133. https://doi.org/10.1089/thy.2015.0020


 

Forms

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