NMO/AQP4 FACS, CSF NMOFC

Synonyms	NMOCSF AQP4 Optic Neuritis Antibody
Allscripts (AEHR) Order Name	NMO/AQP4 FACS, CSF
Sunrise Clinical Manager (SCM) Order Name	Not Orderable
EPIC Order Name	CSF, Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay
Clinical Info	Mayo code: NMOFC Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy Distinguishing NMOSD from multiple sclerosis early in the course of disease When the results of this assay require further evaluation, NMOTC / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay Titer, Spinal Fluid will be performed at an additional charge.
Specimen Type	CSF
Specimen Volume	3 mL CSF (2mL min)
Container	Sterile
Collection Instructions	Container/Tube: Sterile Vial Specimen: 3 mL CSF (2mL min) Transport Temperature: Refrigerated Stability: 72 Hours Room Temperature 28 Days Refrigerated or Frozen
Transport Instructions	Refrigerated
Specimen Stability	72 Hours Room Temperature 28 Days Refrigerated or Frozen
Methodology	Flow Cytometry This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
Days Performed	TAT: 6 - 9 Days
Performing Laboratory	Mayo Clinic Laboratories in Rochester
CPT	86053 86053-titer if required)
PDM	1759172
Result Interpretation Reference Range: Negative A positive value is consistent with a neuromyelitis optica spectrum disorder (NMOSD) and justifies initiation of appropriate immunosuppressive therapy at the earliest possible time. This allows early initiation and maintenance of optimal therapy. This autoantibody is not found in healthy subjects.
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