Celiac HLA DQ Association HLADQ

Synonyms
Allscripts (AEHR) Order Name	Celiac HLA DQ Association
Sunrise Clinical Manager (SCM) Order Name	Celiac HLA DQ Association
EPIC Order Name	Celiac HLA DQ Association
Clinical Info	Aids in the diagnosis of celiac disease. The HLA DQ Association test provides genotyping for detection of HLA-DQ2 (DQA105:01 or 05:05 and DQB102:01 or 02:02) and HLA-DQ8 (DQB103:02). Patients with DQ2, half DQ2 and/or DQ8 are predisposed to celiac disease. A negative result essentially rules out celiac disease. In addition to DQ2 and DQ8 status, the report also includes complete DQA and DQB genotypes, homozygosity for DQB102, and genetic risk assessment.
Specimen Type
Container	Lavender Top Tube
Collection Instructions	Container/Tube: Lavender EDTA tube Specimen: 7 mL whole Blood (3mL min) Transport Temperature: Room Temperature Protect from extreme heat or cold. Limitations The HLA DQ Association test detects celiac disease-associated alleles that predispose to the disorder but is not diagnostic of celiac disease. More than 95% of celiac disease patients are positive for DQ2, half DQ2, or DQ8, but many individuals with these genetic results do not develop celiac disease. Even with appropriate precautions, an occasional specimen may not be satisfactory for testing. In such cases, fresh specimens should be collected for retesting.
Transport Instructions	Room Temperature Protect from extreme heat or cold.
Specimen Stability
Methodology	Polymerase chain reaction (PCR)/sequence-specific oligonucleotide probes (Luminex®) This is a class II antigen level and an allele level test.
Days Performed	TAT 4- 8 Days
Performing Laboratory	LabCorp of America
CPT	81377 x 2
PDM	1559863
Result Interpretation See Report Includes HLA DQ2 and HLA DQ8
Forms