Bile Acids Fractionated BILEFRACT

Synonyms

Allscripts (AEHR) Order Name

Bile Acids Fractionation

Sunrise Clinical Manager (SCM) Order Name

Bile Acids Fractionated

EPIC Order Name

Bile Acids, Fractionated and Total, LC/MS-MS

Clinical Info

This assay uses LC/MS-MS to quantify the free acid, glycine-conjugate and taurine-conjugate forms of cholic acid, chenodeoxycholic acid, deoxycholic acid, and ursodeoxycholic acid. Bile acids may be measured to investigate obstructive cholestasis in pregnancy.
In addition, bile acids are required for cholesterol absorption, fat-soluble vitamin absorption, and to provide resistance to overgrowth of intestinal bacteria. Bile acid levels may be reduced or elevated due to various genetic defects.
 

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

 Container/Tube:  Gold ot Red top tube
Specimen: 1 ml Serum ( 0.3 ml min)
Transport Temperature: Frozen
Stability: 3 Day Refrigerated
                  7 days Frozen
 
Note:  Patient should be fasting 

Transport Instructions

Frozen

Specimen Stability

3 Day Refrigerated
                  7 days Frozen
 
Note:  Patient should be fasting 

Methodology

High-pressure liquid chromatography/tandem mass spectrometry (HPLC/MS-MS)
 
Test includes: Ursodeoxycholic Acids, Cholic Acids, Chenodeoxycholic Acids, Deoxycholic Acids,
 Total Bile Acids

Days Performed

Performing Laboratory

Labcorp-Esoterix

CPT

82542

PDM

5951800

Result Interpretation

Ursodeoxycholic Acids         All Ages: <1.9 umol/L
       
Cholic Acids                          All Ages: <2.2   umol/L
 
Chenodeoxycholic Acids       All Ages:  <5.8 umol/L
 
Deoxycholic Acids                 All Ages: <3.3  umol/L
 
Total Bile Acids                      All Ages: <9.  umol/L
 
 
TAT : 5 - 7 Days
 

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