Inpatient and Outpatient Orderable

Bile Acids, Fractionated and Total, LC/MS-MS

Synonyms

BILE ACIDS FRACTIONATED
BILEFRACT
LAB10857

Cerner Name

Clinical Info

This assay uses LC/MS-MS to quantify the free acid, glycine-conjugate and taurine-conjugate forms of cholic acid, chenodeoxycholic acid, deoxycholic acid, and ursodeoxycholic acid. Bile acids may be measured to investigate obstructive cholestasis in pregnancy.
In addition, bile acids are required for cholesterol absorption, fat-soluble vitamin absorption, and to provide resistance to overgrowth of intestinal bacteria. Bile acid levels may be reduced or elevated due to various genetic defects.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 ml Serum ( 0.3 ml min)

Container

Gold Top Tube

Collection Instructions

Container/Tube: Gold ot Red top tube
Specimen: 1 ml Serum ( 0.3 ml min)
Transport Temperature: Frozen
Stability: 3 Day Refrigerated
7 days Frozen

Note: Patient should be fasting

Transport Instructions

Frozen

Specimen Stability

3 Day Refrigerated
7 days Frozen

Note: Patient should be fasting

Methodology

High-pressure liquid chromatography/tandem mass spectrometry (HPLC/MS-MS)

Test includes: Ursodeoxycholic Acids, Cholic Acids, Chenodeoxycholic Acids, Deoxycholic Acids,
Total Bile Acids

Days Performed

Performing Laboratory

Labcorp-Esoterix

CPT

82542

PDM

5951800

Only Orderable at Locations:

Orderable Everywhere

Results

Component Name	Base Name	Common Name	External Name
URSODEOXYCHOLIC ACIDS	URSODEOXYCH	URSODEOXYCHOLIC ACIDS	Ursodeoxycholic Acids
CHOLIC ACID	CHOLICACID	CHOLIC ACID	Cholic Acid
CHENDEOXYCHOLIC ACID	CHENDEOXY	CHENDEOXYCHOLIC ACID	Chendeoxycholic Acid
DEOXYCHOLIC ACID	DEOXYACID	DEOXYCHOLIC ACID	Deoxycholic Acid
BILE ACIDS TOTAL	BILE	BILE ACIDS TOTAL	Bile Acids Total

Result Interpretation

Ursodeoxycholic Acids         All Ages: <1.9 umol/L

Cholic Acids                          All Ages: <2.2   umol/L

Chenodeoxycholic Acids      All Ages: <5.8 umol/L

Deoxycholic Acids                 All Ages: <3.3 umol/L

Total Bile Acids                     All Ages: <9. umol/L

TAT : 5 - 7 Days

Forms

LAB10857

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