Cytochrome P450 2C19 Genotype CYP2C19GEN
Synonyms |
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Allscripts (AEHR) Order Name |
Cytochrome p450 2C19 Genotype |
Sunrise Clinical Manager (SCM) Order Name |
Cytochrome P450 2C19 Genotype |
Clinical Info |
Cytochrome P450 2C19 (CYP2C19) is a drug-metabolizing enzyme involved in the metabolism of several clinically important drugs including the platelet aggregation inhibitor clopidogrel, the tricyclic antidepressants amitriptyline and nortriptyline, the selective serotonin reuptake inhibitors citalopram and sertraline, and some proton pump inhibitors including omeprazole and pantoprazole. |
Specimen Type |
Blood |
Container |
Lavender Top Tube |
Collection Instructions |
Container/Tube: Lavender top or Yellow ACD Tube |
Transport Instructions |
Room Temperature |
Specimen Stability |
Room temperature Whole Blood: 28 days |
Methodology |
DNA analysis is performed by allele-specific real-time polymerase chain reactions (RT-PCR) to detect single-nucleotide polymorphisms (SNPs) within the CYP2C19 gene and to assign variant CYP2C19 *2, *3, *4, *5, *6, *7, *8, *9, *10, *17 and *35 alleles. *1 denotes detection of the reference (wild-type) sequence at the assessed alleles. No other variants in this gene are detected by this assay. |
Days Performed |
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Performing Laboratory |
Monogram Biosciences Inc |
CPT |
81225 |
PDM |
5906087 |
Result InterpretationSee Report TAT: 8-11 Days |
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Forms |
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