FoundationOne Heme Foundation1HEME

Synonyms

Allscripts (AEHR) Order Name

FoundationOne Heme

Sunrise Clinical Manager (SCM) Order Name

FoundationOne Heme

EPIC Order Name

FoundationOne Heme

Clinical Info

FoundationOne Heme is a comprehensive genomic profiling test that analyzes over 400 DNA and 250 RNA genes to detect substitutions, insertion and deletion alterations (indels), copy number alterations (CNAs), select gene rearrangements, and genomic signatures including microsatellite instability (MSI) and tumor mutational burden (TMB) in patients with hematologic malignancies and solid tumors.

Specimen Type

Blood, Bone Marrow, Tissue

Specimen Volume

Container

EDTA (lavender-top) tube and PAXgene Blood RNA Tube
or
FFPE Tissue (Block or Slides)

Collection Instructions

For Peripheral Whole Blood
This requires 2 tubes. Collect blood in EDTA (lavender-top) tube AND PAXgene Blood RNA Tube 
For Bone Marrow Aspirate
Collect bone marrow aspirate in the  EDTA (lavender-top) tube only.

Transport Instructions

Ship at ambient room temperature
Peripheral blood and bone marrow aspirate samples must be received within 3 days of collection to prevent degradation.

Specimen Stability

3 days at room temperature

Methodology

Hybrid capture-based next-generation sequencing

Days Performed

Performing Laboratories

• Foundation Medicine

CPT

PDM

255299

Result Interpretation

Forms

• FoundationOne_Heme_Specimen Collection Instructions