ExPeCT Expansion & Persistence of CAR T CAR T

Synonyms
Allscripts (AEHR) Order Name	ExPeCT Expansion & Persistence of CAR T
Sunrise Clinical Manager (SCM) Order Name	ExPeCT Expansion & Persistence of CAR T
EPIC Order Name	ExPeCT Expansion and Persistence of CAR T
Clinical Info	For Hematology/Oncology patients this assay provides interventional data which may provide information on the expansion and persistence of the genetically modified T-cells used as therapeutic treatment for specific lymphomas and leukemias (Chimeric Antigen Receptor T-cell therapy or CAR T). However, some patients fail CAR-T therapy due to lack of cell expansion or persistence. Eurofins Viracor has developed and validated a multiplexed quantitative real-time PCR (qPCR) assay targeting the single chain variable fragment (scFv) FMC63 for the longitudinal monitoring of CD19-directed CAR T-cell therapy.
Specimen Type	Blood
Specimen Volume	2 mL Whole Blood ( 0.5 ml min)
Container	Lavender top Tube
Collection Instructions	Container/Tube: Lavender Top Tube Specimen: 2 mL Whole Blood (0.5 mL min)
Transport Instructions	Room Temperature
Specimen Stability	7 Days Room Temperature 7 Days Refrigerated 186 Days (6 months) Frozen
Methodology	Real-Time PCR
Days Performed	TAT: 2 - 4 Days
Performing Laboratory	Viracor-Eurofins
CPT	80299
PDM	245309
Result Interpretation 2.072 to 1.392 x 10⁷ CAR vector copies/µg DNA 100.0 to 6.250 x 10⁸ CAR vector copies/mL DNA
Forms

Synonyms