Inpatient and Outpatient Orderable

ExPeCT Expansion and Persistence of CAR T

Synonyms

  • EXPECT EXPANSION & PERSISTENCE OF CAR T
  • LAB4149

Cerner Name

ExPeCT Expansion & Persistence of CAR T

Clinical Info

For Hematology/Oncology patients this assay provides interventional data which may provide information on the expansion and persistence of the genetically modified T-cells used as therapeutic treatment for specific lymphomas and leukemias (Chimeric Antigen Receptor T-cell therapy or CAR T). However, some patients fail CAR-T therapy due to lack of cell expansion or persistence. Eurofins Viracor has developed and validated a multiplexed quantitative real-time PCR (qPCR) assay targeting the single chain variable fragment (scFv) FMC63 for the longitudinal monitoring of CD19-directed CAR T-cell therapy. 

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

Lavender top Tube

Collection Instructions

Container/Tube:  Lavender Top Tube
Specimen: 2 mL Whole Blood (0.5 mL min)

Specimen Volume

2 mL Whole Blood ( 0.5 ml min)

Transport Instructions

Room Temperature

Specimen Stability

7 Days Room Temperature
7 Days Refrigerated
 186 Days (6 months) Frozen

Methodology

Real-Time PCR

Days Performed

TAT: 2 - 4 Days

Performing Laboratory

Viracor-Eurofins

CPT

80299

PDM

245309

Only Orderable at Locations:

Orderable Everywhere

Results
Component Name Base Name Common Name External Name
CAR VECTOR COPIES/UG CARVECUG CAR VECTOR COPIES/UG CAR vector copies/ug
CAR VECTOR COPIES/ML CARVECML CAR VECTOR COPIES/ML CAR vector copies/mL

Result Interpretation

2.072 to 1.392 x 107 CAR vector copies/µg DNA

100.0 to 6.250 x 108 CAR vector copies/mL DNA

Forms
LAB4149 build edit