Osmotic Fragility, RBC OSM FRAG

Synonyms

Allscripts (AEHR) Order Name

Osmotic Fragility, RBC

Sunrise Clinical Manager (SCM) Order Name

Osmotic Fragility, Erythrocytes

EPIC Order Name

Osmotic Fragility, Erythrocyte

Clinical Info

Functional testing of red blood cell sensitivity to osmotic stress. Do not use to distinguish between spherocytes 
in hereditary spherocytosis and acquired autoimmune hemolytic anemia.

Specimen Type

Blood

Container

Green Top Tube

Collection Instructions

Specimens must arrive Monday through Thursday.
Container/Tube: Green-top (sodium heparin) tube
Specimen: 5 mL (1 mL min ) whole blood
Transport Temperature: Refrigerated

Transport Instructions

Refrigerated

Specimen Stability

Unacceptable Room Temperature
3 Days Refrigerated
Unacceptable Frozen

Methodology

Spectrophotometry

Days Performed

TAT: 2 - 6 Days

Performing Laboratory

ARUP Laboratories

CPT

85555
LOINC Code: 34964-7

PDM

5910815

Result Interpretation

Normal osmotic fragility

Interpretive data:

For patients with acute hemolysis, a normal red cell osmotic fragility

test result cannot exclude an osmotic fragility abnormality since the

osmotically labile cells may be hemolyzed and not present. Recommend

testing during a state of prolonged homeostasis with stable hematocrit.

Forms