Osmotic Fragility, Erythrocyte Build info

Synonyms

• OSMOTIC FRAGILITY, RBC
• ERYTHROCYTES
• RED BLOOD CELLS
• Osmotic Fragility, RBC
• LAB1134

Procedure Name

OSMOTIC FRAGILITY, RBC

Procedure Master Number

LAB1134

Procedure ID

56378

Clinical Info

Functional testing of red blood cell sensitivity to osmotic stress. Do not use to distinguish between spherocytes 
in hereditary spherocytosis and acquired autoimmune hemolytic anemia.

Specimen Sources

Specimen Types

Container

Green Top Tube

Collection Instructions

Specimens must arrive Monday through Thursday.
Container/Tube: Green-top (sodium heparin) tube
Specimen: 5 mL (1 mL min ) whole blood
Transport Temperature: Refrigerated

Specimen Volume

Transport Instructions

Refrigerated

Specimen Stability

Unacceptable Room Temperature
3 Days Refrigerated
Unacceptable Frozen

Methodology

Spectrophotometry

Days Performed

TAT: 2 - 6 Days

Performing Laboratory

ARUP Laboratories

CPT

85555
LOINC Code: 34964-7

PDM

Only Orderable at Locations:

Results

Result Interpretation

Normal osmotic fragility

Interpretive data:

For patients with acute hemolysis, a normal red cell osmotic fragility

test result cannot exclude an osmotic fragility abnormality since the

osmotically labile cells may be hemolyzed and not present. Recommend

testing during a state of prolonged homeostasis with stable hematocrit.

Forms