Inpatient and Outpatient Orderable

Osmotic Fragility, Erythrocyte

Synonyms

ERYTHROCYTES
LAB1134
OSMOTIC FRAGILITY, RBC
Osmotic Fragility, RBC
RED BLOOD CELLS

Cerner Name

Clinical Info

Functional testing of red blood cell sensitivity to osmotic stress. Do not use to distinguish between spherocytes
in hereditary spherocytosis and acquired autoimmune hemolytic anemia.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

Green Top Tube

Collection Instructions

Specimens must arrive Monday through Thursday.
Container/Tube: Green-top (sodium heparin) tube
Specimen: 5 mL (1 mL min ) whole blood
Transport Temperature: Refrigerated

Specimen Volume

Transport Instructions

Refrigerated

Specimen Stability

Unacceptable Room Temperature
3 Days Refrigerated
Unacceptable Frozen

Methodology

Spectrophotometry

Days Performed

TAT: 2 - 6 Days

Performing Laboratory

ARUP Laboratories

CPT

85555
LOINC Code: 34964-7

PDM

5910815

Only Orderable at Locations:

Orderable Everywhere

Results

Component Name	Base Name	Common Name	External Name
OFRR	OFRR	OFRR	Osmotic Fragility

Result Interpretation

Normal osmotic fragility

Interpretive data:

For patients with acute hemolysis, a normal red cell osmotic fragility

test result cannot exclude an osmotic fragility abnormality since the

osmotically labile cells may be hemolyzed and not present. Recommend

testing during a state of prolonged homeostasis with stable hematocrit.

Forms

LAB1134

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