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Serum Protein Electrophoresis

Synonyms

  • LAB119
  • PROTEIN ELECTROPHORESIS, SERUM
  • SPE
  • SPEP

Cerner Name

Protein elect/interp/reflx

Clinical Info


Aids in the diagnosis and monitoring of monoclonal gammopathies, when used in conjunction with serum free light chain analysis. This test alone is not considered an adequate screen for monoclonal gammopathies.
Immunofixation is performed if patterns observed in protein electrophoresis are monoclonal or suspicious.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

1 mL of serum

Container

Gold Top Tube

Collection Instructions

Container/Tube:  Gold-top tube(s)
Specimen:  1 mL of serum

Transport Instructions

Refrigerate

Specimen Stability

Unacceptable Room Temperature
10 Days Refrigerated
30 Days Frozen

Methodology

Capillary Electrophoresis

Days Performed

Monday through Friday

Performing Laboratories

Northwell Health Laboratories

CPT

84165

PDM

5300265

Results
Component Name Base Name Common Name External Name
TOTAL PROTEIN PROT PROTEIN TOTAL Total Protein
TOTAL PROTEIN, SPE TOTALPROTSP TOTAL PROTEIN, SPE Total Protein, SPE
ALBUMIN, SPE ALBUMINSPE ALBUMIN SPE Albumin, SPE
ALPHA 1 GLOBULIN FRACTION ALPHA1 ALPHA 1 Alpha 1 Globulin Fraction
ALPHA 2 GLOBULIN FRACTION ALPHA2 ALPHA 2 Alpha 2 Globulin Fraction
BETA GLOBULIN FRACTION BETAGLOB BETA GLOBULIN Beta Globulin Fraction
GAMMA GLOBULIN FRACTION BETA2 GAMMA GLOBULIN Gamma Globulin Fraction
M-SPIKE MSPIKE M SPIKE M-Spike
SERUM PROTEIN ELECTROPHORESIS INTERP SPEP SPEP INTERP SPE Interpretation
% ALBUMIN SPE PCTALBUR PCT ALBUMIN % Albumin, SPE
% ALPHA 1 SPE ALPHA1PCT ALPHA 1 PCT % Alpha 1 Globulin Fraction, SPE
% ALPHA 2 SPE ALPHA2PCT ALPHA 2 PCT % Alpha 2 Globulin Fraction, SPE
% GAMMA SPE GAMMAPCT GAMMA PCT % Gamma Globulin Fraction, SPE
% BETA SPE BETAPCT BETA PCT % Beta Globulin Fraction, SPE
ALBUMIN/GLOBULIN SPE AGRATIO A G RATIO Albumin/Globulin Ratio
% M SPIKE MSPIKEPCT M SPIKE PCT % M-Spike, SPE

Result Interpretation

 

Fraction Capillary Electrophoresis
Albumin g/dL   3.6 – 5.5
Alpha1 g/dL 0.1 – 0.4
Alpha2 g/dL 0.5 – 1.0
Beta g/dL 0.5 – 1.0
Gamma g/dL 0.6 – 1.6

 

Forms
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Workgroup: Chemistry
Procedure Master Number: LAB119
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