Synonyms
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Cerner Name
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Rapid AML Panel
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Clinical Info
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Use
Mutations in the FLT3 gene are common mutations in acute myeloid leukemia (AML). This assay detects internal tandem duplication (ITD) mutations and mutations in the tyrosine kinase domain (TKD) of FLT3. Presence of these mutations in AML provide prognostic information and can aid in the
determination of therapeutic regimen.
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Specimen Sources
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Bone Marrow
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Specimen Types
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Blood
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Specimen Volume
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3-5 mL whole blood or 1-2 mL bone marrow
Minimum Volume: 3 mL whole blood or 1 mL bone marrow
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Container
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Lavender-top (EDTA) tube OR green-top (sodium heparin)
tube
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Collection Instructions
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Lavender-top (EDTA) tube OR green-top (sodium heparin)
tube whole blood or bone marrow
Causes for Rejection
Specimen does not meet collection criteria; frozen
whole blood, marrow or cell pellet; leaking tube; clotted blood or marrow;
grossly hemolyzed specimen or otherwise visibly degraded; contamination by
another specimen; specimens containing suspicious foreign material
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Transport Instructions
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Room temperature
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Specimen Stability
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Specimen should
arrive in the laboratory within 48 hours of collection.
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Methodology
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FLT3: Polymerase chain reaction (PCR); restriction
enzyme digest; capillary electrophoresis
NPM1: Polymerase chain reaction (PCR); capillary
electrophoresis
IDH1/2 SNaPshot: Multiplex PCR (primer extension-based
method)
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Days Performed
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TAT:4-6 Days
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Performing Laboratories
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CPT
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81120,81121,81245,81246,81310
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PDM
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255569
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Results
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| Component Name |
Base Name |
Common Name |
External Name |
| FLT3 ITD RESULT |
FTL3ITD |
FLT3 ITD RESULT |
Rapid AML Panel |
| FLT3 D835 RESULT |
FLT3D835 |
FLT3 D835 RESULT |
FLT3 D835 Result |
| FLT3 ITD BACKGROUND |
FLT3ITDBKGRD |
FLT3 ITD BACKGROUND |
FLT3 ITD Background |
| FLT3 ITD METHOD |
FLT3ITDMETHD |
FLT3 ITD METHOD |
FLT3 ITD Method |
| FLT3 ITD REFERENCES |
FLT3ITDREF |
FLT3 ITD REFERENCES |
FLT3 ITD References |
| DIRECTOR REVIEW: |
DIRREV |
DIRECTOR REVIEW |
Director Review: |
| NPM1 MUTATION ANALYSIS RESULT: |
NPM1RESULT |
NPM1 MUTATION ANALYSIS RESULT |
NPM1 Mutation Analysis Result: |
| NPM1 BACKGROUND |
NPM1BKGRD |
NPM1 BACKGROUND |
NPM1 Background |
| METHODOLOGY: |
METHOD |
METHODOLOGY |
Methodology |
| REFERENCES |
REFERENCES |
REFERENCES |
References |
| DIRECTOR REVIEW |
DIRREV |
DIRECTOR REVIEW |
Director Review |
| IDH1 RESULT |
IDH1RESULT |
IDH1 RESULT |
IDH1 Result |
| IDH1 NUC CHANGE |
IDH1NUCCHG |
IDH1 NUC CHANGE |
IDH1 Nuc Change |
| IDH1 AMINO ACID CHANGE |
IDH1AACHG |
IDH1 AMINO ACID CHANGE |
IDH1 Amino Acid Change |
| IDH2 RESULT |
IDH2RESULT |
IDH2 RESULT |
IDH2 Result |
| IDH2 NUC CHANGE |
IDH2NUCCHG |
IDH2 NUC CHANGE |
IDH2 Nuc Change |
| IDH2 AMINO ACID CHANGE |
IDH2AACHG |
IDH2 AMINO ACID CHANGE |
IDH2 Amino Acid Change |
| RAPID AML INDICATION |
RAPIDAMLIND |
RAPID AML INDICATION |
Rapid AML Indication |
| LOCATION |
LOCATION |
LOCATION |
Location: |
| SPECIMEN TYPE |
SPECTYPE |
SPECIMEN TYPE |
Specimen Type |
| BLOCK ID |
BLOCKID |
BLOCK ID |
Block Id |
| RAPID AML BACKGROUND |
RAPIDAMLBKGD |
RAPID AML BACKGROUND |
Rapid AML Background |
| METHOD |
METHOD |
METHOD |
Method |
| REFERENCES |
REFERENCES |
REFERENCES |
References |
| DIRECTOR REVIEW |
DIRREV |
DIRECTOR REVIEW |
Director Review |
| MICRODISSECTION PERFORMED |
MICRODISSPER |
MICRODISSECTION PERFORMED |
Microdissection Performed |
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Result Interpretation
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Forms
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