Beta-Amyloid 42/40 Ratio Build info

Synonyms

  • BETA-AMYLOID 42/40 RATIO
  • ABETA42/40
  • BETAAMYOID
  • LAB14288

Short Name

BETA-AMYLOID 42/40 RATIO

Procedure Master Number

LAB14288

Procedure ID

184764

Clinical Info

This LC-MS/MS assay measures beta-amyloid 40 (AB40) as well as AB42 in plasma, rather than AB42 alone. This permits the normalization of beta amyloid levels circulating in plasma in different patients. Using the ratio of beta-amyloid 42/beta-amyloid 40, improves sensitivity and specificity for detecting Alzheimer's disease.

Specimen Type

Blood

Container

Lavender Top Tube

Collection Instructions

Container/Tube:  Lavender Top Tube
Specimen; 1.2 mL plasma 9 0.6 mL min)
Collection Instructions; Spin and separate plasma from cells within one hour of collection.

Transport Instructions

Frozen

Specimen Stability

Unacceptable  Room Temperature
3 Days Refrigerated
32 Days Frozen

Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Days Performed

TAT: 5-7 Days

Performing Laboratory

Quest Diagnostics Nichols Institute San Juan Capistrano CA

CPT

82233
82234

PDM

245767

Results
Component Name Base Name Common Name External Name
ABETA 40 ABETA ABETA 40 Abeta 40
ABETA 42 ABETA ABETA 42 Abeta 42
ABETA 42/40 RATIO ABETA ABETA 42/40 RATIO Abeta 42/40 Ratio