Joint Fluid Pathogen Panel, Molecular Detection

Synonyms

  • HIP
  • JOINT INFECTION, INFECTED JOINT, SYNOVIAL
  • JOINT PCR
  • JOINT PCR PANEL
  • KNEE
  • LAB11813
  • PCR JOINTF INFECTION
  • PROSTHETIC
  • SEPTIC ARTHRITIS
  • SHOULDER
  • SYNOVIAL
  • SYNOVIUM

Cerner Name

Joint PCR Panel

Clinical Info


This is a multiplex PCR which detects the following organisms/resistance genes in infected joint fluid: Anaerococcus prevotii/vaginalis, Clostridium perfringens, 
Cutibacterium avidum/granulosum, Enterococcus faecalis (including VRE), Enterococcus faecium (including VRE), Finegoldia magna, Parvimonas micra, Peptoniphilus spp., 
Peptostreptococcus anaerobius, Staphylococcus aureus (including MRSA), Staphylococcus lugdunensis, Streptococcus pyogenes (GAS), Streptococcus agalactiae (GBS), 
Streptococcus pneumoniae, other Streptococcus species at the genus level, Bacteroides fragilis, Citrobacter spp., Enterobacter cloacae complex, Escherichia coli, 
Haemophilus influenzae, Kingella kingae, Klebsiella aerogenes, Klebsiella pneumoniae group, Morganella morganii, Neisseria gonorrhoeae, Proteus spp., Pseudomonas 
aeruginosa, Salmonella spp., Serratia marcescens, Candida albicans, other Candida species at the genus level, Carbapenemases (KPC, OXA-48-like, NDM, VIM, IMP) and
Extended Spectrum Beta-Lactamases (CTX-M).
Please indicate Specimen Type/Source (Knee, hip, etc) when ordering.  The Joint PCR Panel is intended as an aid to diagnosis of infected joint.  The assay detects 
multiple bacteria and yeast organisms, and should be utilized in conjunction with a Joint Culture.  Lab results should interpreted in the context of the patient's clinical 
presentation, history, and other tests.      

Specimen Sources

Ankle, Left Ankle, Right Elbow, Left Elbow, Right Finger, Left Finger, Right Foot, Left Foot, Right Hand, Left Hand, Right Hip, Left Hip, Right Jaw, Left Jaw, Right Joint Knee, Left Knee, Right Shoulder, Left Shoulder, Right Toe, Left Toe, Right Vertebra Wrist, Left Wrist, Right Show more...

Specimen Types

Aspirate Body Fluid

Specimen Volume

Container

Sterile

Collection Instructions

Sterilely transfer at least 0.5 mL synovial fluid into a sterile screw top container or tube. This may be combined with sample for Joint Culture.  
But should be sent separately from other other synovial fluid tests such as cell count, etc. .  

Transport Instructions

Refrigerate (2-8 C)

Specimen Stability

Refrigerate (2-8 C) 3 days; Frozen (-20 C or lower) for longer storage

Methodology

Mutliplex Nucleic Acid Amplification by Polymerase Chain Reaction

Days Performed

Monday to Sunday

Performing Laboratories
  • Lenox Hill Laboratory
  • Northwell Health -LNP

CPT

87999

PDM

237266

Results
Component Name Base Name Common Name External Name
JOINT PCR SOURCE JNTPCRSRC JOINT PCR SOURCE Joint PCR Source
JOINT PCR PANEL JOINTPCR JOINT PCR PANEL Joint PCR Panel
ANAEROCOCCUS PREVOTII/VAGINALIS ANAERPREVVAG ANAEROCOCCUS PREVOTII VAGINALIS Anaerococcus prevotii/vaginalis
CLOSTRIDIUM PERFRINGENS CLOSTRIDIUMP CLOSTRIDIUM PERFRINGENS Clostridium perfringens
CUTIBACTERIUM AVIDUM/GRANULOSUM CUTIBACAVIGR CUTIBACTERIUM AVIDUM GRANULOSUM Cutibacterium avidum/granulosum
ENTEROCOCCUS FAECALIS ENTERFAECA ENTEROCOCCUS FAECALIS Enterococcus faecalis
ENTEROCOCCUS FAECALIS (VRE) ENTERFAECAV ENTEROCOCCUS FAECALIS VRE Enterococcus faecalis (VRE)
ENTEROCOCCUS FAECIUM ENTERFAECI ENTEROCOCCUS FAECIUM Enterococcus faecium
ENTEROCOCCUS FAECIUM (VRE) ENTERFAECIV ENTEROCOCCUS FAECIUM VRE Enterococcus faecium (VRE)
FINEGOLDIA MAGNA FINEGOLDMA FINEGOLDIA MAGNA Finegoldia magna
PARVIMONAS MICRA PARVMICRA PARVIMONAS MICRA Parvimonas micra
PEPTONIPHILUS SPP. PEPTONIPHSPP PEPTONIPHILUS SPP Peptoniphilus species
PEPTOSTREPTOCOCCUS ANAEROBIUS PEPTSTREPANA PEPTOSTREPTOCOCCUS ANAEROBIUS Peptostreptococcus anaerobius
STAPHYLOCOCCUS AUREUS STAPHYAUREUS STAPHY AUREUS Staphylococcus aureus (MSSA)
METHICILLIN RESISTANT S. AUREUS (MRSA) MRSA METHICILLIN RESISTANT S AUREUS MRSA Methicillin Resistant S. aureus (MRSA)
STAPHYLOCOCCUS LUGDUNENSIS STAPHA STAPHYLOCOCCUS LUGDUNENSIS Staphylococcus lugdunensis
STREPTOCOCCUS SPP. STREPSPP STREPTOCOCCUS SP Streptococcus species
STREPTOCOCCUS AGALACTIAE. STREPAGAL STREPAGAL, AGALACTIAE Streptococcus agalactiae
STREPTOCOCCUS PNEUMONIAE. STREPPNEUM STREPPNEUM, PNEUMONIAE Streptococcus pneumoniae
STREPTOCOCCUS PYOGENES RAPSCRN STREPTOCOCCUS PYOGENES Streptococcus pyogenes
BACTEROIDES FRAGILIS BACTERFRAG BACTEROIDES FRAGILIS Bacteroides fragilis
CITROBACTER SPP. CITROBACTER CITROBACTER SPP Citrobacter spp.
ENTEROBACTER CLOACAE COMPLEX ENTERBCLCO ENTEROBACTER CLOACAE COMPLEX Enterobacter cloacae complex
ESCHERICHIA COLI ESCHERCOLI ESCHERICHIA COLI Escherichia coli
HAEMOPHILUS INFLUENZAE. HAEMINFL HAEMOPHILUS INFLUENZAE Haemophilus influenzae
KINGELLA KINGAE KINGKING KINGELLA KINGAE Kingella kingae
KLEBSIELLA AEROGENES KLEBAEROG KLEBSIELLA AEROGENES Klebsiella aerogenes
KLEBSIELLA PNEUMONIAE GROUP KLEBPNEUM KLEBSIELLA PNEUMONIAE GROUP Klebsiella pneumoniae group
MORGANELLA MORGANII MORGANMORG MORGANELLA MORGANII Morganella morganii
NEISSERIA GONORRHOEAE NGONORRH NEISSERIA GONORRHOEAE Neisseria gonorrhoeae
PROTEUS SPP. PROSPP PROTEUS SPP Proteus species
PSEUDOMONAS AERUGINOSA PSEUDOMONAS PSEUDOMONAS AERUGINOSA Pseudomonas aeruginosa
SALMONELLA SPP. SALSPP SALMONELLA SPP Salmonella species
SERRATIA MARCESCENS SERMARCES SERRATIA MARCESCENS Serratia marcescens
CANDIDA SPP. CANDIDASPP CANDIDA SPP Candida species
CANDIDA ALBICANS CANDIDAALB CANDIDA ALBICANS Candida albicans
IMP (CARBAPENEMASE) IMP IMP CARBAPENEMASE IMP (Carbapenemase)
KPC (CARBAPENEMASE) KPC KPC CARBAPENEMASE KPC (Carbapenemase)
NDM (CARBAPENEMASE) NDM NDM CARBAPENEMASE NDM (Carbapenemase)
OXA-48-LIKE (CARBAPENEMASE) CARBAPENEM OXA 48 LIKE CARBAPENEMASE OXA-48-like (Carbapenemase)
VIM (CARBAPENEMASE) VIM VIM CARBAPENEMASE VIM (Carbapenemase)
CTX-M CTXM CTX M CTX-M
ESBL ESBL ESBL ESBL
CARBAPENEM CARBAPENEM CARBAPENEM Carbapenem resistance

Result Interpretation

Please indicate Specimen Type/Source (Knee, hip, etc) when ordering.  Assays results should always interpreted in the context of the patient's clinical presentation, history, and other tests.  Detected targets may represent nonviable organisms or skin flora.  Panel targets do not include Staphylococcus epidermidis, other coagulase negative Staphylococci, or Cutibacterium.  Joint Culture is recommended in conjunction with Joint PCR to help identify organisms absent from panel and for antibiotic susceptiblity testing.        

Table of Joint Panel Targets

Gram Positive Bacteria Gram Negative Bacteria Yeast
Anaerococcus prevotii/vaginalis  Bacteroides fragilis  Candida
Clostridium perfringens  Citrobacter  Candida albicans
Cutibacterium avidum/granulosum  Enterobacter cloacae complex   
Enterococcus faecalis  Escherichia coli  Resistance Genes
Enterococcus faecium  Haemophilus influenzae  CTX-M 
Finegoldia magna  Kingella kingae  KPC 
Parvimonas micra  Klebsiella aerogenes  NDM 
Peptoniphilus  Klebsiella pneumoniae group  vanA/B
Peptostreptococcus anaerobius  Morganella morganii  IMP 
Staphylococcus aureus Neisseria gonorrhoeae mecA/C and MREJ (MRSA) 
Staphylococcus lugdunensis Proteus spp. OXA-48-like 
Streptococcus spp. Pseudomonas aeruginosa VIM
Streptococcus pyogenes Salmonella spp.  
Streptococcus agalactiae Serratia marcescens  
Streptococcus pneumoniae    

Forms
ID Molecular LAB11813 build edit