GeneDx = 410

Prenatal Targeted Chromosomal Microarray

Prenatal Targeted Chromosomal Microarray

Abnormal fetal ultrasound findings Ambiguous chromosome results Suspected deletion/duplication syndrome Family history of known or suspected chromosome imbalances Abnormal maternal serum screening Advanced maternal age The prenatal targeted CMA focuses on detection of CNVs in approximately 150 cytogenetically relevant regions, including common or novel microdeletion  and microduplication syndromes. Deletions >1 Mb and duplications >2 Mb in the remainder of the genome are also assessed. In addition, SNP probes  covering only chromosomes known to contain imprinted regions (specifically, chromosomes 6, 7, 11, 14, 15, and 20) can provide information regarding ROH and UPD on those chromosomes.

Sterile

Note: Diagnosis must be indicated on request Prenatal Chorionic Villi, Amniotic Fluid, Cultured cells  Container/Tube:  Sterile transport tube  Specimen:    Chronic Villi 5 - 10 mg                        Amniotic Fluid 10 - 15 mL                        Cultured cells   2 T-25 flasks                        3 Ug DNA Concentration   Transport Temperature:  Room Temperature or Refrigerated Additionally, please send: Parental blood specimens  1 Lavender top EDTA tube for maternal confirmation studies or if parental specimens are needed for testing and result interpretation    

Room Temperature or Refrigerated

7 Days Refrigerated Blood samples older than 7 days can still be shipped, they will be tested if the yield and quality of DNA permit

Targeted Chromosomal Microarray

TAT: 14 Days on Direct specimen If direct was not possible and cultured cells are prepared add 7-14 Days

GeneDx-Sema4

81229 81265

1659897