Inpatient and Outpatient Orderable

BCL2-IGH Gene Rearrangement Build info

Synonyms

  • BCL2-IGH GENE REARRANGEMENT
  • BCL2IGH GENE
  • LAB11274

Procedure Name

BCL2-IGH GENE REARRANGEMENT

Procedure Master Number

LAB11274

Procedure ID

114912

Clinical Info

Is useful for establishing clonality of B-cell neoplasms and in the identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a B-cell neoplasm. It can be used in association with the immunoglobulin kappa light chain

Specimen Sources

 Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous Bone Marrow Aspirate

Specimen Types

 Blood Bone Marrow

Container

Lavender-top (EDTA) tube, or Sodium Heparin (Dark Green), or
Tissue in Lymph Node Transport bottle or
Fine Needle Aspirates(FNA)

Collection Instructions

Specimen: Whole blood, bone marrow, fresh or frozen tissue, fixed-cell pellet 7 mL whole blood, 2 mL bone marrow  or 0.5 g tissue ( 3 mL whole blood min)
Collection Instructions
Do not reject specimens, send to laboratory for screening.
8 unstained sections on glass slides labeled with surgical case number (pathology report required, indicate if fixative is not formalin) Please include pathology report for frozen tissue and FFPE cases (partial/preliminary reports acceptable).
Needle washings (acceptable): in alcohol based fixative (eg. CytoLyt) are acceptable).

Specimen Volume

Whole blood, bone marrow, fresh or frozen tissue, fixed-cell pellet 7 mL whole blood, 2 mL bone marrow,or 0.5 g tissue ( 3 mL whole blood min)

Transport Instructions

Room Temperature- Blood or Slides
Frozen Fresh Tissue only

Specimen Stability

Whole blood/Bone marrow Room temperature: 7 days
                                           Refrigerated: 7 days
                                           Frozen: Unacceptable
Formalin-fixed Paraffin-embedded tissue block (acceptable) Room temperature: Indefinitely
                                           Refrigerated: Indefinitely
                                           Frozen: Unacceptable
Fresh, unfixed tissue- Frozen -70 1 year

Methodology

Polymerase Chain Reaction (PCR) • Fragment Analysis

Days Performed

TAT: 6-7 Days

Performing Laboratory

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

CPT

81261
84999

PDM

 1859733

Only Orderable at Locations:

 Orderable Everywhere

Results
Component Name Base Name Common Name External Name
CLINICAL INDICATION: CLININD CLINICAL INDICATION Clinical Indication:
SPECIMEN SOURCE. SPECSRCE SPECIMEN SOURCE Specimen Source
BLOCK/SPECIMEN ID BLOCKSPECID BLOCK SPECIMEN ID Block/Specimen ID
BCL2IGH IGH RESULT IGHRES BCL2IGH IGH RESULT IGH Result
IGH FR1 IGHFR1 IGH FR1 IGH FR1
IGH FR2 IGHFR2 IGH FR2 IGH FR2
IGH FR3 IGHFR3 IGH FR3 IGH FR3
PATHOLOGIST INTERP PATHOLINTER PATHOLOGIST INTERP Pathologist Interp

Result Interpretation

See Report

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

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