BCL2-IGH Gene Rearrangement

BCL2-IGH Gene Rearrangement

Is useful for establishing clonality of B-cell neoplasms and in the identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a B-cell neoplasm. It can be used in association with the immunoglobulin kappa light chain

Blood, Tissue, Other

Lavender-top (EDTA) tube, or Sodium Heparin (Dark Green), or Tissue in Lymph Node Transport bottle or Fine Needle Aspirates(FNA)

Specimen: Whole blood, bone marrow, fresh or frozen tissue, fixed-cell pellet 7 mL whole blood, 2 mL bone marrow  or 0.5 g tissue ( 3 mL whole blood min) Collection Instructions Do not reject specimens, send to laboratory for screening. 8 unstained sections on glass slides labeled with surgical case number (pathology report required, indicate if fixative is not formalin) Please include pathology report for frozen tissue and FFPE cases (partial/preliminary reports acceptable). Needle washings (acceptable): in alcohol based fixative (eg. CytoLyt) are acceptable).

Room Temperature- Blood or Slides Frozen Fresh Tissue only

Whole blood/Bone marrow Room temperature: 7 days                                            Refrigerated: 7 days                                            Frozen: Unacceptable Formalin-fixed Paraffin-embedded tissue block (acceptable) Room temperature: Indefinitely                                            Refrigerated: Indefinitely                                            Frozen: Unacceptable Fresh, unfixed tissue- Frozen -70 1 year

Polymerase Chain Reaction (PCR) • Fragment Analysis

TAT: 6-7 Days

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

81261 84999

1859733