BCL2-IGH Gene Rearrangement Build info

Synonyms

• BCL2-IGH GENE REARRANGEMENT
• BCL2IGH GENE
• LAB11274

Short Name

BCL2-IGH GENE REARRANGEMENT

Procedure Master Number

LAB11274

Procedure ID

114912

Clinical Info

Is useful for establishing clonality of B-cell neoplasms and in the identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a B-cell neoplasm. It can be used in association with the immunoglobulin kappa light chain

Specimen Sources

Specimen Types

Container

Lavender-top (EDTA) tube, or Sodium Heparin (Dark Green), or
Tissue in Lymph Node Transport bottle or
Fine Needle Aspirates(FNA)

Collection Instructions

Specimen: Whole blood, bone marrow, fresh or frozen tissue, fixed-cell pellet 7 mL whole blood, 2 mL bone marrow  or 0.5 g tissue ( 3 mL whole blood min)
Collection Instructions
Do not reject specimens, send to laboratory for screening.
8 unstained sections on glass slides labeled with surgical case number (pathology report required, indicate if fixative is not formalin) Please include pathology report for frozen tissue and FFPE cases (partial/preliminary reports acceptable).
Needle washings (acceptable): in alcohol based fixative (eg. CytoLyt) are acceptable).

Transport Instructions

Room Temperature- Blood or Slides
Frozen Fresh Tissue only

Specimen Stability

Whole blood/Bone marrow Room temperature: 7 days
                                           Refrigerated: 7 days
                                           Frozen: Unacceptable
Formalin-fixed Paraffin-embedded tissue block (acceptable) Room temperature: Indefinitely
                                           Refrigerated: Indefinitely
                                           Frozen: Unacceptable
Fresh, unfixed tissue- Frozen -70 1 year

Methodology

Polymerase Chain Reaction (PCR) • Fragment Analysis

Days Performed

TAT: 6-7 Days

Performing Laboratory

Quest Diagnostics' Nichols Institute, Inc. - Chantilly

CPT

81261
84999

PDM

Only Orderable at Locations:

Results