Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum
Test Catalog Information
| Test Catalog Synonyms | |
| EPIC Synonyms |
LGI1AB LGI1 Ab IGG CBA-IFA with Refelx to Titer |
| Cerner Primary Mnemonic | LGI1 Ab IGG CBA-IFA with Refelx to Titer |
| EPIC Display Name | Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum |
| Allscripts (AEHR) Order Name | LGI1 Ab IGG CBA-IFA with Refelx to Titer |
| Sunrise Clinical Manager (SCM) Order Name | LGI1 Ab IgG by CBA-IFA w/Rflx to Titer |
| EPIC Inpatient Orderable | Yes |
| EPIC Outpatient Orderable | Yes |
| Cerner Results |
LGI1 Ab IgG Screen by IFA LGI1 Ab IgG Titer by IFA |
| Clinical Info |
Aid in diagnosis of leucine-rich glioma inactivated 1 protein (LGI1) antibody disorders associated with limbic encephalitis, hyponatremia, and myoclonic movements. Disorders are rarely associated with tumors. Use to manage antibody-positive (LGI1) individual following immunotherapy and/or plasmapheresis Leucine-rich, glioma-inactivated 1 protein (LGI1) IgG antibody may occur as part of the voltage-gated potassium channel (VGKC) complex antibodies. The presence of LGI1 IgG antibody is mainly associated with limbic encephalitis, hyponatremia and myoclonic movements. LGI1 IgG antibody is rarely associated with tumors but may occur infrequently in Morvan syndrome, neuromyotonia and idiopathic epilepsy. The full-spectrum of clinical disorders associated with the LGI1 IgG antibody continues to be defined. Results should be interpreted in correlation with the patient's clinical history and other laboratory findings. This indirect fluorescent antibody assay utilizes leucine-rich, glioma-inactivated 1 protein (LGI1) transfected cell lines for the detection and semi-quantification of the LGI1 IgG antibody. |
| Specimen Type |
Blood |
| Container |
Gold Top Tube |
| Collection Instructions |
Container/Tube: Gold top tube Specimen: 1 mL serum ( 0.2 mL min) Transport Temperature: Refrigerated Note: Separate serum from cells within 2 hours of collection |
| Transport Instructions |
Refrigerated |
| Specimen Stability |
2 Days Room Temperature 14 Days Refrigerated Year Frozen |
| Methodology |
Semi-Quantitative Indirect Fluorescent Antibody |
| Days Performed |
TAT: 2-9 Days |
| Performing Laboratory |
ARUP Laboratories |
| CPT |
86255 Reflex titer 86256 LOINC Code: 82978-8 |
| PDM |
1859768 |
Desired Epic Build Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum
| Cerner Primary Mnemonic: | LGI1 Ab IGG CBA-IFA with Refelx to Titer | |||||||||
| PDM | 1859768 | |||||||||
| Informatics - Workgroup | Immunology | |||||||||
| Synonyms * | LGI1AB LGI1 Ab IGG CBA-IFA with Refelx to Titer | |||||||||
| Display Name * | Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum | |||||||||
| Order Entry Specimen Sources * | ||||||||||
| Order Entry Specimen Types |
Blood
| |||||||||
| Specimen Navigator Specimen Types | ||||||||||
| Specimen Navigator Specimen Sources | ||||||||||
| Specimen Navigator Short Name | ||||||||||
| Ordering info (EPIC SmartText) | Aid in diagnosis of leucine-rich glioma inactivated 1 protein (LGI1) antibody disorders associated with limbic encephalitis, hyponatremia, and myoclonic movements. Disorders are rarely associated with tumors. Use to manage antibody-positive (LGI1) individual following immunotherapy and/or plasmapheresis Leucine-rich, glioma-inactivated 1 protein (LGI1) IgG antibody may occur as part of the voltage-gated potassium channel (VGKC) complex antibodies. The presence of LGI1 IgG antibody is mainly associated with limbic encephalitis, hyponatremia and myoclonic movements. LGI1 IgG antibody is rarely associated with tumors but may occur infrequently in Morvan syndrome, neuromyotonia and idiopathic epilepsy. The full-spectrum of clinical disorders associated with the LGI1 IgG antibody continues to be defined. Results should be interpreted in correlation with the patient's clinical history and other laboratory findings. This indirect fluorescent antibody assay utilizes leucine-rich, glioma-inactivated 1 protein (LGI1) transfected cell lines for the detection and semi-quantification of the LGI1 IgG antibody. | |||||||||
| IP Orderable | Yes | |||||||||
| OP Orderable | Yes | |||||||||
|
AOEs * | ||||||||||
| AP AOEs | ||||||||||
| Special History | No | |||||||||
| Build Comments | ||||||||||
| Filter * | ||||||||||
| Procedure Category Change | ||||||||||
Cerner Results
| ||||||||||
Actual Epic build
| Procedure Id | 114514 | ||||||||||||||||||
| Pdm | 1859768 | ||||||||||||||||||
| Order Display Name | Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum | ||||||||||||||||||
| Procedure Name | LGI1 AB IGG BY CBA-IFA W/RFLX TO TITER | ||||||||||||||||||
| Procedure Master Number | LAB11055 | ||||||||||||||||||
| Short Procedure Name | LGI1 AB IGG BY CBA-IFA W/RFLX TO TITER | ||||||||||||||||||
| Category Code | 1.0 | ||||||||||||||||||
| Category Code Record Name | LAB BLOOD ORDERABLES | ||||||||||||||||||
| Synonyms | LGI1AB LGI1 AB IGG CBA-IFA WITH REFELX TO TITER | ||||||||||||||||||
| Clinically Active | Yes | ||||||||||||||||||
| Orderable | Yes | ||||||||||||||||||
| Performable | Yes | ||||||||||||||||||
| Filter Genomics | |||||||||||||||||||
| Reference Link Url | https://labs.northwell.edu/epic/test/114514 | ||||||||||||||||||
| Ordering Instructions | |||||||||||||||||||
| Default Specimen Type | Blood | ||||||||||||||||||
| Specimen Type Pick List | Blood | ||||||||||||||||||
| Specimen Type List | |||||||||||||||||||
| Op Specimen Type List | |||||||||||||||||||
| Specimen Source Pick List | Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous | ||||||||||||||||||
| Specimen Source Default - Male | Blood, Venous | ||||||||||||||||||
| Specimen Source Default - Female | Blood, Venous | ||||||||||||||||||
| Specimen Source List | |||||||||||||||||||
| Op Specimen Source List | |||||||||||||||||||
| Ip Lab Test Components For Report | |||||||||||||||||||
| Op Lab Test Components For Report | |||||||||||||||||||
| Order Questions | [] | ||||||||||||||||||
| Order Questions Record Name | |||||||||||||||||||
| Inpatient Order Questions | [] | ||||||||||||||||||
| Inpatient Order Questions Record Name | |||||||||||||||||||
| Order Specific Question Override | |||||||||||||||||||
| Inpatient Question Override | |||||||||||||||||||
| Location Restrict List Ip | |||||||||||||||||||
| Location Restrict List Ip Record Name | |||||||||||||||||||
| Location Restrict List Include Ip | |||||||||||||||||||
| Location Restrict List Op | |||||||||||||||||||
| Location Restrict List Op Record Name | |||||||||||||||||||
| Location Restrict List Includes Op | |||||||||||||||||||
| Edp Amb Order Specific Questions Record Name | |||||||||||||||||||
| Edp Ip Order Specific Questions Record Name | |||||||||||||||||||
| Edp Ip Specimen Source | Blood, Venous Blood, Central Line Blood, Arterial Blood, Capillary | ||||||||||||||||||
| Edp Op Specimen Source | |||||||||||||||||||
| Edp Ip Specimen Type | Blood | ||||||||||||||||||
| Edp Op Specimen Type | |||||||||||||||||||
| Derived Edp Ip Buttons S | Blood, Capillary Blood, Venous Blood, Central Line Blood, Arterial | ||||||||||||||||||
| Derived Edp Ip Buttons T | Blood | ||||||||||||||||||
| Derived Edp Op Buttons S | |||||||||||||||||||
| Derived Edp Op Buttons T | |||||||||||||||||||
| Ip Orderable | 1 | ||||||||||||||||||
| Op Orderable | 1 | ||||||||||||||||||
| EPIC OP AOEs | |||||||||||||||||||
| EPIC IP AOEs | |||||||||||||||||||
EPIC Components (results)
| |||||||||||||||||||