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Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum

Desired Epic Build * = editable field  

Cerner Primary Mnemonic: LGI1 Ab IGG CBA-IFA with Refelx to Titer
PDM 1859768
Informatics - WorkgroupImmunology
Synonyms *LGI1AB
LGI1 Ab IGG CBA-IFA with Refelx to Titer
Display Name *Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum
Specimen Sources (combined Order Entry and Specimen Navigator) *
Specimen Types (combined Order Entry and Specimen Navigator) *
Blood
Body Fluids (types sent through AOEs)
Specimen Navigator Specimen Types
Specimen Navigator Specimen Sources
Specimen Navigator Short Name
Ordering info (EPIC SmartText)Aid in diagnosis of leucine-rich glioma inactivated 1 protein (LGI1) antibody disorders associated with limbic encephalitis, hyponatremia, and myoclonic movements.  Disorders are rarely associated with tumors. Use to manage antibody-positive (LGI1) individual following immunotherapy and/or plasmapheresis   Leucine-rich, glioma-inactivated 1 protein (LGI1) IgG antibody may occur as part of the voltage-gated potassium channel (VGKC) complex antibodies.   The presence of LGI1 IgG antibody is mainly associated with limbic encephalitis, hyponatremia and myoclonic movements. LGI1 IgG antibody is rarely  associated with tumors but may occur infrequently in Morvan syndrome, neuromyotonia and idiopathic epilepsy. The full-spectrum of clinical disorders  associated with the LGI1 IgG antibody continues to be defined. Results should be interpreted in correlation with the patient's clinical history and other  laboratory findings. This indirect fluorescent antibody assay utilizes leucine-rich, glioma-inactivated 1 protein (LGI1) transfected cell lines for the detection  and semi-quantification of the LGI1 IgG antibody.  
IP Orderable (inpatient) Yes
OP Orderable (outpatient) Yes
AOEs *

AP AOEs
Special History No
Build Comments
Filter *
Cerner Site RestrictARUP Laboratory
Cerner Results

Result Desc Result display Result PDM
LGI1 Ab IgG Screen by IFA LGI1ABGSCN 1759386A
LGI1 Ab IgG Titer by IFA LGI1ABGTR 1759386B

Actual Epic Build 3/11/2025

PROCEDURE ID 114514
PDM 1859768
ORDER DISPLAY NAME Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG CBA-IFA with Reflex to Titer, Serum
PROCEDURE NAME LGI1 AB IGG BY CBA-IFA W/RFLX TO TITER
PROCEDURE MASTER NUMBER LAB11055
SHORT PROCEDURE NAME LGI1 AB IGG BY CBA-IFA W/RFLX TO TITER
CATEGORY CODE 1.0
CATEGORY CODE RECORD NAME LAB BLOOD ORDERABLES
SYNONYMS LGI1AB
LGI1 AB IGG CBA-IFA WITH REFELX TO TITER
CLINICALLY ACTIVE Yes
ORDERABLE Yes
PERFORMABLE Yes
FILTER GENOMICS
REFERENCE LINK URL https://labs.northwell.edu/epic/test/114514
ORDERING INSTRUCTIONS
DEFAULT SPECIMEN TYPE Blood
SPECIMEN TYPE PICK LIST Blood
SPECIMEN TYPE LIST
OP SPECIMEN TYPE LIST
SPECIMEN SOURCE PICK LIST Blood, Arterial
Blood, Capillary
Blood, Central Line
Blood, Venous
SPECIMEN SOURCE DEFAULT - MALE Blood, Venous
SPECIMEN SOURCE DEFAULT - FEMALE Blood, Venous
SPECIMEN SOURCE LIST
OP SPECIMEN SOURCE LIST
IP LAB TEST COMPONENTS FOR REPORT LG1ABIGGSC
LG1ABIGGT
OP LAB TEST COMPONENTS FOR REPORT LG1ABIGGSC
LG1ABIGGT
ORDER QUESTIONS []
ORDER QUESTIONS RECORD NAME
INPATIENT ORDER QUESTIONS []
INPATIENT ORDER QUESTIONS RECORD NAME
ORDER SPECIFIC QUESTION OVERRIDE
INPATIENT QUESTION OVERRIDE
LOCATION RESTRICT LIST IP
LOCATION RESTRICT LIST IP RECORD NAME
LOCATION RESTRICT LIST INCLUDE IP
LOCATION RESTRICT LIST OP
LOCATION RESTRICT LIST OP RECORD NAME
LOCATION RESTRICT LIST INCLUDES OP
EDP AMB ORDER SPECIFIC QUESTIONS RECORD NAME
EDP IP ORDER SPECIFIC QUESTIONS RECORD NAME
EDP IP SPECIMEN SOURCE Blood, Venous
Blood, Central Line
Blood, Arterial
Blood, Capillary
EDP OP SPECIMEN SOURCE
EDP IP SPECIMEN TYPE Blood
EDP OP SPECIMEN TYPE
DERIVED EDP IP BUTTONS S Blood, Central Line
Blood, Arterial
Blood, Capillary
Blood, Venous
DERIVED EDP IP BUTTONS T Blood
DERIVED EDP OP BUTTONS S
DERIVED EDP OP BUTTONS T
IP ORDERABLE 1
OP ORDERABLE 1
STANDARD LAB COMPONENTS
STANDARD LAB COMPONENTS RECORD NAME
COMPONENT DATA REQUIREMENT
EPIC OP AOEs

EPIC IP AOEs

EPIC Components (results - crosswalked through Cerner)

Component IDComponent NameBase NameCommon NameExternal NameCerner Result PDM
3047803275.0 LGI1 AB IGG SCREEN BY IFA LG1ABIGGSC LGI1 AB IGG SCREEN BY IFA 1759386A
3047803276.0 LGI1 AB IGG TITER BY IFA LG1ABIGGT LGI1 AB IGG TITER BY IFA 1759386B