Inpatient and Outpatient Orderable

c-KIT Mutation Analysis in Tumors of Hematopoietic Tissue Build info

Synonyms

  • C-KIT MUTATION ANALYSIS
  • KITB
  • LAB11023

Procedure Name

C-KIT MUTATION ANALYSIS

Procedure Master Number

LAB11023

Procedure ID

114452

Clinical Info

c-KIT is a proto-oncogene that encodes a type III transmembrane tyrosine kinase. c-KIT and its ligand stem cell factor have a key role in survival, proliferation, differentiamyeloid leukemia (AML), and approximately 20% high-grade myelodysplastic syndrome (MDS) and MDS-derived AML. c-KIT mutation in AML confers increased risk of relapse and decreased overall survival. 
 

Specimen Sources

 Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

 Blood

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender EDTA tube or Green Sodium Heparin tube
Specimen: 3 - 5 mL Whole Blood or 2 mL Bone Marrow (3 mL blood and 1 mL Bone Marrow min)
Transport Temperature: Room Temperature
Stability: 3 Days Room Temperature
7 Days Refrigerated

Specimen Volume

3 - 5 mL Whole Blood or 2 mL Bone Marrow (3 mL blood and 1 mL Bone Marrow min)

Transport Instructions

Room Temperature

Specimen Stability

3 Days Room Temperature
7 Days Refrigerated

Methodology

Polymerase chain reaction (PCR) and DNA sequencing

Days Performed

LabCorp Test code 480940
TAT: 11-15 Days

Performing Laboratory

LabCorp

CPT

81272

PDM

 2059793

Only Orderable at Locations:

 Orderable Everywhere

Results
Component Name Base Name Common Name External Name
C-KIT MA ANALYSIS RESULT CKITMARES C KIT MA ANALYSIS RESULT c-KIT Mutation Analysis Result
C-KIT AMINO ACID CHANGE CKITAA C KIT AMINO ACID CHANGE c-KIT Amino Acid Change
C-KIT NUCLEOTIDE CHANGE CKITNC C KIT NUCLEOTIDE CHANGE c-KIT Nucleotide Change
C-KIT BACKGROUND CKITBG C KIT BACKGROUND c-KIT Background
C-KIT REFERENCE CKITREF C KIT REFERENCE c-KIT Reference
C-KIT METHODOLOGY CKITMETHOD C KIT METHODOLOGY c-KIT Methodology
C-KIT DISCLAIMER CKITDISC C KIT DISCLAIMER c-KIT Disclaimer
C-KIT DIRECTOR CKITDIR C KIT DIRECTOR c-KIT Director Review

Result Interpretation

See Report
 
TAT: 11- 15 Days

Forms
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