c-KIT Mutation Analysis in Tumors of Hematopoietic Tissue Build info

Synonyms

  • C-KIT MUTATION ANALYSIS
  • KITB
  • LAB11023

Short Name

C-KIT MUTATION ANALYSIS

Procedure Master Number

LAB11023

Procedure ID

114452

Clinical Info

c-KIT is a proto-oncogene that encodes a type III transmembrane tyrosine kinase. c-KIT and its ligand stem cell factor have a key role in survival, proliferation, differentiamyeloid leukemia (AML), and approximately 20% high-grade myelodysplastic syndrome (MDS) and MDS-derived AML. c-KIT mutation in AML confers increased risk of relapse and decreased overall survival. 
 

Specimen Type

Blood, Bone Marrow

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender EDTA tube or Green Sodium Heparin tube
Specimen: 3 - 5 mL Whole Blood or 2 mL Bone Marrow (3 mL blood and 1 mL Bone Marrow min)
Transport Temperature: Room Temperature
Stability: 3 Days Room Temperature
7 Days Refrigerated

Transport Instructions

Room Temperature

Specimen Stability

3 Days Room Temperature
7 Days Refrigerated

Methodology

Polymerase chain reaction (PCR) and DNA sequencing

Days Performed

LabCorp Test code 480940
TAT: 11-15 Days

Performing Laboratory

LabCorp

CPT

81272

PDM

2059793

Results
Component Name Base Name Common Name External Name
C-KIT DIRECTOR CKIT C KIT DIRECTOR C-Kit Director
C-KIT DISCLAIMER CKIT C KIT DISCLAIMER C-Kit Disclaimer
C-KIT AMINO ACID CHANGE CKIT C KIT AMINO ACID CHANGE C-Kit Amino Acid Change
C-KIT NUCLEOTIDE CHANGE CKIT C KIT NUCLEOTIDE CHANGE C-Kit Nucleotide Change
C-KIT REFERENCE CKIT C KIT REFERENCE C-Kit Reference
C-KIT MA ANALYSIS RESULT CKIT C KIT MA ANALYSIS RESULT C-Kit Ma Analysis Result
C-KIT METHODOLOGY CKIT C KIT METHODOLOGY C-Kit Methodology
C-KIT BACKGROUND CKIT C KIT BACKGROUND C-Kit Background