c-KIT Mutation Analysis in Tumors of Hematopoietic Tissue c-KIT

Synonyms

Allscripts (AEHR) Order Name

c-KIT Mutation Analysis

Sunrise Clinical Manager (SCM) Order Name

c-KIT Mutation Analysis

Clinical Info

c-KIT is a proto-oncogene that encodes a type III transmembrane tyrosine kinase. c-KIT and its ligand stem cell factor have a key role in survival, proliferation, differentiamyeloid leukemia (AML), and approximately 20% high-grade myelodysplastic syndrome (MDS) and MDS-derived AML. c-KIT mutation in AML confers increased risk of relapse and decreased overall survival. 
 

Specimen Type

Blood, Bone Marrow

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender EDTA tube or Green Sodium Heparin tube
Specimen: 3 - 5 mL Whole Blood or 2 mL Bone Marrow (3 mL blood and 1 mL Bone Marrow min)
Transport Temperature: Room Temperature
Stability: 3 Days Room Temperature
7 Days Refrigerated

Transport Instructions

Room Temperature

Specimen Stability

3 Days Room Temperature
7 Days Refrigerated

Methodology

Polymerase chain reaction (PCR) and DNA sequencing

Days Performed

LabCorp Test code 480940
TAT: 11-15 Days

Performing Laboratory

LabCorp

CPT

81272

PDM

2059793

Result Interpretation

See Report
 
TAT: 11- 15 Days

Forms


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