PML/RARA Quantitative, PCR

Synonyms

• LAB10898
• PROMYELOCYTIC LEUKEMIA/RETINOIC ACID RECEPTOR A

Cerner Name

PML/RARA Quantitative, PCR

Clinical Info

Diagnosis of acute promyelocytic leukemia (APL)

Detection of residual or recurrent APL

Monitoring the level of promyelocytic leukemia/retinoic acid receptor alpha (PML/RARA) in APL patients

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous Bone Marrow Bone Marrow Aspirate

Specimen Types

Aspirate Blood Bone Marrow

Specimen Volume

Container

Lavender Top Tube

Collection Instructions

Submit only 1 of the following specimens:

Specimen Type: Whole blood
Container/Tube:
Preferred: 2 EDTA (lavender top)
Acceptable: ACD (yellow top)
Specimen Volume: 10 mL (8 mL min)
Collection Instructions:
1. Invert several times to mix blood.
2. Send specimen in original tube.
3. Label specimen as blood.

Specimen Type: Bone marrow
Container/Tube:
Preferred: EDTA (lavender top)
Acceptable: ACD (yellow top)
Specimen Volume: 4 mL (2 mL min)
Collection Instructions:
1. Invert several times to mix bone marrow.
2. Send specimen in original tube.
3. Label specimen as bone marrow.
Stability: 5 days Refrigerated (preferred)
72 hours Ambient

Transport Instructions

Specimen Stability

5 days Refrigerated (preferred)
72 hours Ambient

Methodology

Quantitative, Real-Time Polymerase Chain Reaction (PCR)

Days Performed

Monday through Friday
TAT: 5-10 Days

Performing Laboratories

Mayo Medical Laboratories

CPT

81315-PML/RARalpha (t(15;17)), (PML-RARA regulated adaptor
molecule 1) (eg promyelocytic leukemia) translocation analysis; all
breakpoints (eg, intron 3, intron 6 and variable in exon 6),
qualitative or quantitative

PDM

1553720

Results

Result Interpretation

Forms

• Molecular Hematology Tests Specimen Collection Requirements Memo 4-27-2023