Inpatient and Outpatient Orderable

PML/RARA Quantitative, PCR

Synonyms

LAB10898
PROMYELOCYTIC LEUKEMIA/RETINOIC ACID RECEPTOR A

Cerner Name

Clinical Info

Diagnosis of acute promyelocytic leukemia (APL)

Detection of residual or recurrent APL

Monitoring the level of promyelocytic leukemia/retinoic acid receptor alpha (PML/RARA) in APL patients

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

Lavender Top Tube

Collection Instructions

Submit only 1 of the following specimens:

Specimen Type: Whole blood
Container/Tube:
Preferred: 2 EDTA (lavender top)
Acceptable: ACD (yellow top)
Specimen Volume: 10 mL (8 mL min)
Collection Instructions:
1. Invert several times to mix blood.
2. Send specimen in original tube.
3. Label specimen as blood.

Specimen Type: Bone marrow
Container/Tube:
Preferred: EDTA (lavender top)
Acceptable: ACD (yellow top)
Specimen Volume: 4 mL (2 mL min)
Collection Instructions:
1. Invert several times to mix bone marrow.
2. Send specimen in original tube.
3. Label specimen as bone marrow.
Stability: 5 days Refrigerated (preferred)
72 hours Ambient

Specimen Volume

Transport Instructions

Specimen Stability

5 days Refrigerated (preferred)
72 hours Ambient

Methodology

Quantitative, Real-Time Polymerase Chain Reaction (PCR)

Days Performed

Monday through Friday
TAT: 5-10 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

81315-PML/RARalpha (t(15;17)), (PML-RARA regulated adaptor
molecule 1) (eg promyelocytic leukemia) translocation analysis; all
breakpoints (eg, intron 3, intron 6 and variable in exon 6),
qualitative or quantitative

PDM

1553720

Only Orderable at Locations:

Orderable Everywhere

Results

Component Name	Base Name	Common Name	External Name
PMLR SPECIMEN TYPE	PMLRSPECTY	PMLR SPECIMEN TYPE	PMLR Specimen Type
PMLR FINAL DIAGNOSIS	PMLRFNLDIAG	PMLR FINAL DIAGNOSIS	PMLR Final Diagnosis

Result Interpretation

An interpretive report will be provided.

If positive, a value representing a ratio of PML-RARA fusion transcript to the
control gene ABL1
expressed as a percentage will be reported.

Forms

Molecular Hematology Tests Specimen Collection Requirements Memo 4-27-2023

LAB10898

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