Synonyms
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- LAB10898
- PROMYELOCYTIC LEUKEMIA/RETINOIC ACID RECEPTOR A
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Cerner Name
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PML/RARA Quantitative, PCR
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Clinical Info
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Diagnosis of acute promyelocytic leukemia (APL)
Detection of residual or recurrent APL
Monitoring the level of promyelocytic leukemia/retinoic acid receptor alpha (PML/RARA) in APL patients
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Specimen Sources
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Blood, Arterial
Blood, Capillary
Blood, Central Line
Blood, Venous
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Specimen Types
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Blood
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Specimen Volume
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Container
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Lavender Top Tube
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Collection Instructions
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Submit only 1 of the following specimens:
Specimen Type: Whole blood
Container/Tube:
Preferred: 2 EDTA (lavender top)
Acceptable: ACD (yellow top)
Specimen Volume: 10 mL (8 mL min)
Collection Instructions:
1. Invert several times to mix blood.
2. Send specimen in original tube.
3. Label specimen as blood.
Specimen Type: Bone marrow
Container/Tube:
Preferred: EDTA (lavender top)
Acceptable: ACD (yellow top)
Specimen Volume: 4 mL (2 mL min)
Collection Instructions:
1. Invert several times to mix bone marrow.
2. Send specimen in original tube.
3. Label specimen as bone marrow.
Stability: 5 days Refrigerated (preferred)
72 hours Ambient
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Transport Instructions
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Specimen Stability
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5 days Refrigerated (preferred)
72 hours Ambient
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Methodology
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Quantitative, Real-Time Polymerase Chain Reaction (PCR)
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Days Performed
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Monday through Friday
TAT: 5-10 Days
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Performing Laboratories
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Mayo Medical Laboratories
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CPT
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81315-PML/RARalpha (t(15;17)), (PML-RARA regulated adaptor
molecule 1) (eg promyelocytic leukemia) translocation analysis; all
breakpoints (eg, intron 3, intron 6 and variable in exon 6),
qualitative or quantitative
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PDM
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1553720
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Results
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| Component Name |
Base Name |
Common Name |
External Name |
| PMLR SPECIMEN TYPE |
PMLRSPECTY |
PMLR SPECIMEN TYPE |
PMLR Specimen Type |
| PMLR FINAL DIAGNOSIS |
PMLRFNLDIAG |
PMLR FINAL DIAGNOSIS |
PMLR Final Diagnosis |
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Result Interpretation
An interpretive report will be provided.
If positive, a value representing a ratio of PML-RARA fusion transcript to the
control gene ABL1
expressed as a percentage will be reported.
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Forms
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