CSF, Myelin Basic Protein

Synonyms

• LAB190
• MBP
• MYELIN BASIC PROTEIN, CSF

Cerner Name

MYEL

Clinical Info

Assist in diagnosing multiple sclerosis; determine whether an MS patient is having an active demyelinating episode; determine whether active demyelination is occurring in patients being treated by intrathecal chemotherapy or radiation therapy for neoplastic diseases involving the central nervous system; diagnose acute brain tissue destruction in children, including newborns; assess the efficacy of potential treatments for MS

Specimen Sources

CSF Reservoir Lumbar Puncture VP Shunt Aspirate

Specimen Types

Cerebrospinal Fluid

Specimen Volume

1 mL CSF  ( 0.8 mL min) CSF must be clear-Reject if Hemolysis present.

Container

CSF Tube

Collection Instructions

Container/Tube: Sterile screw-capped, sterile container
Specimen: 1 mL CSF  ( 0.8 mL min) CSF must be clear-Reject if Hemolysis present.
                      Centrifuge CSF at 1500xg for 20 minutes and place the supernatant in a separate tube. Ensure that residual fibrin and cellular matter have been removed prior to transport
Transport Temperature:  Refrigerated
Stability: Room temperature: 7 days                 Refrigerated:            7 days                 Frozen:                   14 days
Patient Preparation   Lumbar puncture should be performed within five days of onset of neurologic symptoms suggestive of multiple sclerosis.

Transport Instructions

Refrigerated

Specimen Stability

Room temperature: 7 days                 Refrigerated:            7 days                 Frozen:                   14 days
Patient Preparation   Lumbar puncture should be performed within five days of onset of neurologic symptoms suggestive of multip

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Days Performed

TAT: 5-8 Days

Performing Laboratories

LabCorp

CPT

83873
 
LOINC Code:  2638-5

PDM

5900070

Results

Result Interpretation

Forms