Urine Free Light Chains (Kappa and Lambda) with Ratio
Desired Epic Build
* = editable field
| Cerner Primary Mnemonic: | Free Kappa/Lambda Urine | ||||||||||||
| PDM | 5905920 | ||||||||||||
| Informatics - Workgroup | Immunology | ||||||||||||
| Synonyms * | Free Kappa and Lambda Light Chains, Urine BENCE - JONES PROTEINS Free Kappa/Lambda Urine FLC | ||||||||||||
| Display Name * | Urine Free Light Chains (Kappa and Lambda) with Ratio | ||||||||||||
| Specimen Sources (combined Order Entry and Specimen Navigator) * | |||||||||||||
| Specimen Types (combined Order Entry and Specimen Navigator) * |
Urine
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| Body Fluids (types sent through AOEs) | |||||||||||||
| Specimen Navigator Specimen Types | |||||||||||||
| Specimen Navigator Specimen Sources | |||||||||||||
| Specimen Navigator Short Name | |||||||||||||
| Ordering info (EPIC SmartText) | This test is a latex-enhanced, immunoassay that provides ultrasensitive detection and quantitation of free light chains (FLCs) in serum or urine earlier than electrophoresis. It is an aid in the diagnosis and treatment of multiple myeloma, lymphocytic neoplasms, Waldenstroms macroglobulinemia, and connective tissue diseases, such as systemic lupus erythematosus. Approximately 15% of all cases of multiple myeloma produce only free kappa or lambda light chains in excess. These patients frequently show no abnormality on serum protein electrophoresis. Quite often urine is tested for the presence of these light chains, which are also called Bence Jones Proteins. However, the FLCs entering the urine are strongly influenced by renal tubular function. When clonal proliferation of plasma cells starts to develop, the FLC concentration increases in serum. Since these small particles are rapidly cleared by the renal tubules, urine tests for FLCs remain negative until the tumor mass expands, and the FLCs in serum exceed the resorptive capacity of the renal tubules. Therefore, the measurement of FLCs in serum is an alternative to less sensitive urine testing. Changing concentrations of FLCs in serum relate better to changing tumor load than to concentrations in urine. | ||||||||||||
| IP Orderable (inpatient) | Yes | ||||||||||||
| OP Orderable (outpatient) | Yes | ||||||||||||
| AOEs * | |||||||||||||
| AP AOEs | |||||||||||||
| Special History | No | ||||||||||||
| Build Comments | |||||||||||||
| Filter * | |||||||||||||
| Cerner Site Restrict | AML/Quest Labs Northwell Health Laboratories | ||||||||||||
Cerner Results
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Actual Epic Build 3/11/2025
| PROCEDURE ID | 64634 | ||||||||||||||||||||||||
| PDM | 5905920 | ||||||||||||||||||||||||
| ORDER DISPLAY NAME | Urine Free Light Chains (Kappa and Lambda) with Ratio | ||||||||||||||||||||||||
| PROCEDURE NAME | KAPPA / LAMBDA LIGHT CHAINS, URINE, 24 HOUR | ||||||||||||||||||||||||
| PROCEDURE MASTER NUMBER | LAB734 | ||||||||||||||||||||||||
| SHORT PROCEDURE NAME | KAPPA/LAMBDA LIGHT CHAIN | ||||||||||||||||||||||||
| CATEGORY CODE | 6.0 | ||||||||||||||||||||||||
| CATEGORY CODE RECORD NAME | LAB URINE ORDERABLES | ||||||||||||||||||||||||
| SYNONYMS | FREE KAPPA AND LAMBDA LIGHT CHAINS, URINE BENCE - JONES PROTEINS FREE KAPPA/LAMBDA URINE FLC |
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| CLINICALLY ACTIVE | Yes | ||||||||||||||||||||||||
| ORDERABLE | Yes | ||||||||||||||||||||||||
| PERFORMABLE | Yes | ||||||||||||||||||||||||
| FILTER GENOMICS | |||||||||||||||||||||||||
| REFERENCE LINK URL | https://labs.northwell.edu/epic/test/64634 | ||||||||||||||||||||||||
| ORDERING INSTRUCTIONS | |||||||||||||||||||||||||
| DEFAULT SPECIMEN TYPE | Urine | ||||||||||||||||||||||||
| SPECIMEN TYPE PICK LIST | Urine | ||||||||||||||||||||||||
| SPECIMEN TYPE LIST | |||||||||||||||||||||||||
| OP SPECIMEN TYPE LIST | |||||||||||||||||||||||||
| SPECIMEN SOURCE PICK LIST | Urine, Clean Catch Urine, Catheter |
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| SPECIMEN SOURCE DEFAULT - MALE | Urine, Clean Catch | ||||||||||||||||||||||||
| SPECIMEN SOURCE DEFAULT - FEMALE | Urine, Clean Catch | ||||||||||||||||||||||||
| SPECIMEN SOURCE LIST | |||||||||||||||||||||||||
| OP SPECIMEN SOURCE LIST | |||||||||||||||||||||||||
| IP LAB TEST COMPONENTS FOR REPORT | FREEKAPPAUR FREELAMBDA KAPLAMBDAU |
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| OP LAB TEST COMPONENTS FOR REPORT | FREEKAPPAUR FREELAMBDA KAPLAMBDAU |
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| ORDER QUESTIONS | [] | ||||||||||||||||||||||||
| ORDER QUESTIONS RECORD NAME | |||||||||||||||||||||||||
| INPATIENT ORDER QUESTIONS | [] | ||||||||||||||||||||||||
| INPATIENT ORDER QUESTIONS RECORD NAME | |||||||||||||||||||||||||
| ORDER SPECIFIC QUESTION OVERRIDE | |||||||||||||||||||||||||
| INPATIENT QUESTION OVERRIDE | |||||||||||||||||||||||||
| LOCATION RESTRICT LIST IP | |||||||||||||||||||||||||
| LOCATION RESTRICT LIST IP RECORD NAME | |||||||||||||||||||||||||
| LOCATION RESTRICT LIST INCLUDE IP | |||||||||||||||||||||||||
| LOCATION RESTRICT LIST OP | |||||||||||||||||||||||||
| LOCATION RESTRICT LIST OP RECORD NAME | |||||||||||||||||||||||||
| LOCATION RESTRICT LIST INCLUDES OP | |||||||||||||||||||||||||
| EDP AMB ORDER SPECIFIC QUESTIONS RECORD NAME | |||||||||||||||||||||||||
| EDP IP ORDER SPECIFIC QUESTIONS RECORD NAME | |||||||||||||||||||||||||
| EDP IP SPECIMEN SOURCE | Urine, Clean Catch Catheter |
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| EDP OP SPECIMEN SOURCE | |||||||||||||||||||||||||
| EDP IP SPECIMEN TYPE | |||||||||||||||||||||||||
| EDP OP SPECIMEN TYPE | Urine | ||||||||||||||||||||||||
| DERIVED EDP IP BUTTONS S | Urine, Clean Catch | ||||||||||||||||||||||||
| DERIVED EDP IP BUTTONS T | |||||||||||||||||||||||||
| DERIVED EDP OP BUTTONS S | |||||||||||||||||||||||||
| DERIVED EDP OP BUTTONS T | |||||||||||||||||||||||||
| IP ORDERABLE | 1 | ||||||||||||||||||||||||
| OP ORDERABLE | 1 | ||||||||||||||||||||||||
| STANDARD LAB COMPONENTS | |||||||||||||||||||||||||
| STANDARD LAB COMPONENTS RECORD NAME | |||||||||||||||||||||||||
| COMPONENT DATA REQUIREMENT | |||||||||||||||||||||||||
| EPIC OP AOEs | |||||||||||||||||||||||||
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EPIC Components (results - crosswalked through Cerner)
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