Epic Build / Desired Build Test Compendium
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MPL Mutation Molecular Detection Epic Compendium

▶ Desired Epic Build * = editable field

Cerner Primary Mnemonic:	HLX MPL Mutation Analysis Case
PDM	1559701
Informatics - Workgroup	Molpath inhouse
Synonyms *	MPL Mutation Analysis Case MPL Mutation Analysis JAK-2 negative MPN diagnosis, JAK2 V617 negative testing MPLMUT
Display Name *	MPL Mutation Molecular Detection
Specimen Sources (combined Order Entry and Specimen Navigator) *	Bone Marrow
Specimen Types (combined Order Entry and Specimen Navigator) *	Blood Bone Marrow Aspirate
Body Fluids (types sent through AOEs)
Specimen Navigator Specimen Types	Aspirate
Specimen Navigator Specimen Sources	Isthmus Left Nasal No Laterality Right Total Abdomen/Peritoneum Abscess Adrenal Amniotic Sac Anus Appendix Axilla Bile Duct Bone Bone Marrow Brain Breast Bronchial Buccal Colon Duodenum Ear Esophagus Extranodal Lymphoid Eye Fallopian Tube Gallbladder Gingiva Ileum Jejunum Joint Kidney Larynx Liver Lung Lymph Node Mediastinum Meninges/Dura Misc Muscle Nasopharynx Nipple Nose Oropharynx/Throat Ovary Palate Pancreas Pancreatic Duct Parathyroid Paratubal Cyst Pelvic Penis Pericardium Pharynx Pleura Prostate Rectum Retroperitoneum Salivary Gland Sinus Skin Soft Tissue Spleen Stomach Testis Thymus Thyroid Tongue Tonsil Trachea Uterus Vagina Vas Deferens Vascular Vulva Wound Deep
Specimen Navigator Short Name	MPL MUTATION
Ordering info (EPIC SmartText)	The MPL gene is located on chromosome 1p34, it contains 12 exons. MPL mutations lead to a gain of function and receptor activation in the absence of thrombopoietin binding with constitutional activation of the JAK-STAT signaling pathway. The mutations can occur in Essential Thrombcythemia (ET) and Primary Myelofibrosis (PMF) and have not been reported in Polycythemia Vera (PV). The most common pathological variants causing gain of function in the MPL gene are located in exon 10: W515L, W515K, W515A and S505N.
IP Orderable (inpatient)	Yes
OP Orderable (outpatient)	Yes
AOEs *
AP AOEs
Special History	Yes
Build Comments
Filter *	genetics
Cerner Site Restrict
Cerner Results

Actual Epic Build 12/05/2025

PROCEDURE ID

115149

PDM

1559701

ORDER DISPLAY NAME

MPL Mutation Molecular Detection

PROCEDURE NAME

MPL MUTATION

PROCEDURE MASTER NUMBER

LAB11404

SHORT PROCEDURE NAME

MPL Mutation

CATEGORY CODE

21.0

CATEGORY CODE RECORD NAME

LAB MOLECULAR DIAGNOSTICS ORDERABLES

SYNONYMS

MPL MUTATION ANALYSIS CASE
MPL MUTATION ANALYSIS
JAK-2 NEGATIVE MPN DIAGNOSIS, JAK2 V617 NEGATIVE TESTING
MPLMUT

CLINICALLY ACTIVE

Yes

ORDERABLE

Yes

PERFORMABLE

Yes

FILTER GENOMICS

Generic Genomics Procedure

REFERENCE LINK URL

https://labs.northwell.edu/epic/test/115149

ORDERING INSTRUCTIONS

DEFAULT SPECIMEN TYPE

Blood

SPECIMEN TYPE PICK LIST

Bone Marrow
Blood
Aspirate

SPECIMEN TYPE LIST

OP SPECIMEN TYPE LIST

SPECIMEN SOURCE PICK LIST

Bone Marrow Aspirate
Blood, Arterial
Blood, Capillary
Blood, Central Line
Blood, Venous
Bone Marrow

SPECIMEN SOURCE DEFAULT - MALE

Blood, Venous

SPECIMEN SOURCE DEFAULT - FEMALE

Blood, Venous

SPECIMEN SOURCE LIST

OP SPECIMEN SOURCE LIST

IP LAB TEST COMPONENTS FOR REPORT

HLXMPLFR:10

OP LAB TEST COMPONENTS FOR REPORT

HLXMPLFR:10

ORDER QUESTIONS

["3045300170", "3045300171", "3045300173"]

ORDER QUESTIONS RECORD NAME

NH IP HOME COLLECT DATE
NH IP HOME COLLECT DAYS
NH IP HOME COLLECT MEDICALLY NECESSARY

INPATIENT ORDER QUESTIONS

[]

INPATIENT ORDER QUESTIONS RECORD NAME

ORDER SPECIFIC QUESTION OVERRIDE

Yes

INPATIENT QUESTION OVERRIDE

Yes

LOCATION RESTRICT LIST IP

LOCATION RESTRICT LIST IP RECORD NAME

LOCATION RESTRICT LIST INCLUDE IP

LOCATION RESTRICT LIST OP

LOCATION RESTRICT LIST OP RECORD NAME

LOCATION RESTRICT LIST INCLUDES OP

EDP AMB ORDER SPECIFIC QUESTIONS RECORD NAME

NH IP PATIENT COMPLETED CONSENT

EDP IP ORDER SPECIFIC QUESTIONS RECORD NAME

NH IP PATIENT COMPLETED CONSENT

EDP IP SPECIMEN SOURCE

EDP OP SPECIMEN SOURCE

EDP IP SPECIMEN TYPE

EDP OP SPECIMEN TYPE

DERIVED EDP IP BUTTONS S

DERIVED EDP IP BUTTONS T

DERIVED EDP OP BUTTONS S

DERIVED EDP OP BUTTONS T

IP ORDERABLE

OP ORDERABLE

STANDARD LAB COMPONENTS

STANDARD LAB COMPONENTS RECORD NAME

COMPONENT DATA REQUIREMENT

EPIC OP AOEs

Question ID	Question Name	Question	Response Type	Response List	Require Response
3045300170	NH IP HOME COLLECT DATE	Start Date	Date		Yes
3045300171	NH IP HOME COLLECT DAYS	Days	Custom List	Monday Tuesday Wednesday Thursday Friday Saturday Sunday	Yes
3045300173	NH IP HOME COLLECT MEDICALLY NECESSARY	Medically Necessary?	Yes/No		Yes

EPIC IP AOEs

EPIC Components (results - crosswalked through Cerner)

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MPL Mutation Molecular Detection Epic Compendium

▶ Desired Epic Build * = editable field

Actual Epic Build 12/05/2025 Save Test to CSV

Epic Build / Desired Build Test Compendium
Welcome to the new Northwell Health Labs Epic Build / Desired Build Test Directory! Please email ClinicalLabInformatics@northwell.edu with any typos, corrections or issues.

Actual Epic Build 12/05/2025