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Atypical Hemolytic Uremic Syndrome (AHUS) Complement Panel

Desired Epic Build * = editable field  

Cerner Primary Mnemonic: aHUS Complement Panel, S and P
PDM 225440
Informatics - WorkgroupHematology
Synonyms *
Display Name *Atypical Hemolytic Uremic Syndrome (AHUS) Complement Panel
Specimen Sources (combined Order Entry and Specimen Navigator) *
Specimen Types (combined Order Entry and Specimen Navigator) *
Blood
Body Fluids (types sent through AOEs)
Specimen Navigator Specimen Types
Specimen Navigator Specimen Sources
Specimen Navigator Short Name
Ordering info (EPIC SmartText)Detecting deficiencies in the alternative pathway that can cause atypical-hemolytic uremic syndrome, dense deposit disease, and C3 glomerulonephritis ORDERING GUIDANCE This test should be performed prior to treatment initiation and in the absence of therapy with complement inhibitors, such as eculizumab or ravulizumab. Complement inhibitors will affect performance of these assays. For evaluating patients with possible thrombotic microangiopathies (TMA), the recommended first-tier test is ADM13 / ADAMTS13 Activity and Inhibitor Profile, Plasma. This test should be a second-tier test for TMA. For patients who have received eculizumab or need to monitor response to eculizumab therapy, the recommended test is ECUMP / Eculizumab Monitoring Panel, Serum. Soluble membrane attack complex (sMAC) should not be used as a standalone assay to monitor eculizumab efficiency.
IP Orderable (inpatient) Yes
OP Orderable (outpatient) Yes
AOEs *

AOE PDM AOE Display AOE Description Prompt
AOE225440B AHUSEOR Is Eculizumab or Ravulizumab taken? X
AP AOEs

    
Special History No 
 
    
Build Comments

    
Filter *

    
    
Cerner Site RestrictMayo Medical Labs

    
Cerner Results


                

            

                Result Desc
                Result display
                Result PDM
            

                        

                Factor B Complement Antigen, S
                FBCOMAS
                225440G
            

                        

                Complement C3, S
                COMC3S
                225440E
            

                        

                Complement C4, S
                COMC4S
                225440F
            

                        

                Factor H Complement Antigen, S
                FHCOMAS
                225440H
            

                        

                Alternative Complement Path Func, S
                ALTCOMFS
                225440D
            

                        

                Is Eculizumab or Ravulizumab taken?
                AHUSEOR
                225440B
            

                        

                CBb Complement, P
                CBDCOMP
                225440J
            

                        

                AHUS Interpretation
                AHUSINT
                225440A
            

                        

                Complement, Total, S
                COMPTOTS
                225440C
            

                        

                SC5b-9 Complement, P
                SC5B9CP
                225440K
            

                    

            


     





    Actual Epic Build 3/11/2025
    






                

        PROCEDURE ID
        114482
    

        

        PDM
        225440
    

        

        ORDER DISPLAY NAME
        Atypical Hemolytic Uremic Syndrome (AHUS) Complement Panel
    

        

        PROCEDURE NAME
        ATYPICAL HEMOLYTIC UREMIC SYNDROME COMPLEMENT P
    

        

        PROCEDURE MASTER NUMBER
        LAB11038
    

        

        SHORT PROCEDURE NAME
        ATYPICAL HEMOLYTIC UREMIC SYNDROME COMPLEMENT P
    

        

        CATEGORY CODE
        1.0
    

        

        CATEGORY CODE RECORD NAME
        LAB BLOOD ORDERABLES
    

        

        SYNONYMS
        
    

        

        CLINICALLY ACTIVE
        Yes
    

        

        ORDERABLE
        Yes
    

        

        PERFORMABLE
        Yes
    

        

        FILTER GENOMICS
        
    

        

        REFERENCE LINK URL
        https://labs.northwell.edu/epic/test/114482
    

        

        ORDERING INSTRUCTIONS
        
    

        

        DEFAULT SPECIMEN TYPE
        Blood
    

        

        SPECIMEN TYPE PICK LIST
        Blood
    

        

        SPECIMEN TYPE LIST
        
    

        

        OP SPECIMEN TYPE LIST
        
    

        

        SPECIMEN SOURCE PICK LIST
        Blood, Arterial
Blood, Capillary
Blood, Central Line
Blood, Venous		
    

        

        SPECIMEN SOURCE DEFAULT - MALE
        Blood, Venous
    

        

        SPECIMEN SOURCE DEFAULT - FEMALE
        Blood, Venous
    

        

        SPECIMEN SOURCE LIST
        
    

        

        OP SPECIMEN SOURCE LIST
        
    

        

        IP LAB TEST COMPONENTS FOR REPORT
        AHUSINT
MEDTAKEN
COMTOTS
ALTCOMPPATH
C3COMP
C4COMP
FACTORB
FACTORH
CBBCOMP
SC5B9CO		
    

        

        OP LAB TEST COMPONENTS FOR REPORT
        AHUSINT
MEDTAKEN
COMTOTS
ALTCOMPPATH
C3COMP
C4COMP
FACTORB
FACTORH
CBBCOMP
SC5B9CO		
    

        

        ORDER QUESTIONS
        ["3046000027"]
    

        

        ORDER QUESTIONS RECORD NAME
        NH IP AHUSEOR
    

        

        INPATIENT ORDER QUESTIONS
        ["3046000027"]
    

        

        INPATIENT ORDER QUESTIONS RECORD NAME
        NH IP AHUSEOR
    

        

        ORDER SPECIFIC QUESTION OVERRIDE
        
    

        

        INPATIENT QUESTION OVERRIDE
        
    

        

        LOCATION RESTRICT LIST IP
        
    

        

        LOCATION RESTRICT LIST IP RECORD NAME
        
    

        

        LOCATION RESTRICT LIST INCLUDE IP
        
    

        

        LOCATION RESTRICT LIST OP
        
    

        

        LOCATION RESTRICT LIST OP RECORD NAME
        
    

        

        LOCATION RESTRICT LIST INCLUDES OP
        
    

        

        EDP AMB ORDER SPECIFIC QUESTIONS RECORD NAME
        
    

        

        EDP IP ORDER SPECIFIC QUESTIONS RECORD NAME
        
    

        

        EDP IP SPECIMEN SOURCE
        Blood, Venous
Blood, Central Line
Blood, Arterial
Blood, Capillary		
    

        

        EDP OP SPECIMEN SOURCE
        
    

        

        EDP IP SPECIMEN TYPE
        Blood
    

        

        EDP OP SPECIMEN TYPE
        
    

        

        DERIVED EDP IP BUTTONS S
        Blood, Central Line
Blood, Arterial
Blood, Capillary
Blood, Venous		
    

        

        DERIVED EDP IP BUTTONS T
        Blood
    

        

        DERIVED EDP OP BUTTONS S
        
    

        

        DERIVED EDP OP BUTTONS T
        
    

        

        IP ORDERABLE
        1
    

        

        OP ORDERABLE
        1
    

        

        STANDARD LAB COMPONENTS
        
    

        

        STANDARD LAB COMPONENTS RECORD NAME
        
    

        

        COMPONENT DATA REQUIREMENT
        
    

    
    
EPIC OP AOEs


                

            
Question IDQuestion NameQuestionResponse TypeResponse ListRequire Response

                        

                3046000027
                NH IP AHUSEOR
                Is Eculizumab or Ravulizumab taken?
                Custom List
                Yes

No		
                Yes
            

                    

            


    
EPIC IP AOEs


                

            
Question IDQuestion NameQuestionResponse TypeResponse ListRequire Response

                        

                3046000027
                NH IP AHUSEOR
                Is Eculizumab or Ravulizumab taken?
                Custom List
                Yes

No		
                Yes
            

                    

            


    
EPIC Components (results - crosswalked through Cerner)


                

            
Component IDComponent NameBase NameCommon NameExternal NameCerner Result PDM

                        

                3047802388.0
                FACTOR B COMPLEMENT ANTIGEN, S
                FACTORB
                FACTOR B COMPLEMENT ANTIGEN, S
                
                225440G
            

                        

                3047801953.0
                COMPLEMENT C3, S
                C3COMP
                COMPLEMENT C3, S
                
                225440E
            

                        

                3047801954.0
                COMPLEMENT C4, S
                C4COMP
                COMPLEMENT C4, S
                
                225440F
            

                        

                3047802389.0
                FACTOR H COMPLEMENT ANTIGEN, S
                FACTORH
                FACTOR H COMPLEMENT ANTIGEN, S
                
                225440H
            

                        

                3047800975.0
                ALTERNATIVE COMPLEMENT PATH FUNC, S
                ALTCOMPPATH
                ALTERNATIVE COMPLEMENT PATH FUNC, S
                
                225440D
            

                        

                3047803109.0
                IS ECULIZUMAB OR RAVULIZUMAB TAKEN?
                MEDTAKEN
                IS ECULIZUMAB OR RAVULIZUMAB TAKEN
                
                225440B
            

                        

                3047801681.0
                CBB COMPLEMENT, P
                CBBCOMP
                CBB COMPLEMENT, P
                
                225440J
            

                        

                3047800899.0
                ATYPICAL HEMOLYTIC UREMIC SYNDROME INTERPRETATION
                AHUSINT
                ATYPICAL HEMOLYTIC UREMIC SYNDROME INTERPRETATION
                
                225440A
            

                        

                3047801956.0
                COMPLEMENT, TOTAL, S
                COMTOTS
                COMPLEMENT, TOTAL, S
                
                225440C
            

                        

                3047804663.0
                SC5B-9 COMPLEMENT, P
                SC5B9CO
                SC5B 9 COMPLEMENT, P
                
                225440K