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Atypical Hemolytic Uremic Syndrome (AHUS) Complement Panel
Epic Compendium
| Cerner Primary Mnemonic: | aHUS Complement Panel, S and P |
| PDM | 225440 |
| Informatics - Workgroup | Hematology |
| Synonyms * | |
| Display Name * | Atypical Hemolytic Uremic Syndrome (AHUS) Complement Panel |
| Specimen Sources (combined Order Entry and Specimen Navigator) * |
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| Specimen Types (combined Order Entry and Specimen Navigator) * |
Blood
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| Body Fluids (types sent through AOEs) |
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| Specimen Navigator Specimen Types |
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| Specimen Navigator Specimen Sources |
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| Specimen Navigator Short Name | |
| Ordering info (EPIC SmartText) | Detecting deficiencies in the alternative pathway that can cause atypical-hemolytic uremic syndrome, dense deposit disease, and C3 glomerulonephritis
ORDERING GUIDANCE
This test should be performed prior to treatment initiation and in the absence of therapy with complement inhibitors, such as eculizumab or ravulizumab. Complement inhibitors will affect performance of these assays.
For evaluating patients with possible thrombotic microangiopathies (TMA), the recommended first-tier test is ADM13 / ADAMTS13 Activity and Inhibitor Profile, Plasma. This test should be a second-tier test for TMA.
For patients who have received eculizumab or need to monitor response to eculizumab therapy, the recommended test is ECUMP / Eculizumab Monitoring Panel, Serum. Soluble membrane attack complex (sMAC) should not be used as a standalone assay to monitor eculizumab efficiency. |
| IP Orderable (inpatient) | Yes |
| OP Orderable (outpatient) | Yes |
AOEs *
| AOE PDM |
AOE Display |
AOE Description |
Prompt |
| AOE225440B |
Is Eculizumab or Ravulizumab taken? |
Is Eculizumab or Ravulizumab taken? |
X |
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| AP AOEs | |
| Special History | No |
| Build Comments | |
| Filter * | |
| Cerner Site Restrict | Mayo Medical Labs |
Cerner Results
| Result Desc |
Result display |
Result PDM |
| Factor B Complement Antigen, S |
FBCOMAS |
225440G |
| Complement C3, S |
COMC3S |
225440E |
| Complement C4, S |
COMC4S |
225440F |
| Factor H Complement Antigen, S |
FHCOMAS |
225440H |
| Alternative Complement Path Func, S |
ALTCOMFS |
225440D |
| Is Eculizumab or Ravulizumab taken? |
AHUSEOR |
225440B |
| CBb Complement, P |
CBDCOMP |
225440J |
| AHUS Interpretation |
AHUSINT |
225440A |
| Complement, Total, S |
COMPTOTS |
225440C |
| SC5b-9 Complement, P |
SC5B9CP |
225440K |
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| PROCEDURE ID |
114482 |
| PDM |
225440 |
| ORDER DISPLAY NAME |
Atypical Hemolytic Uremic Syndrome (AHUS) Complement Panel |
| PROCEDURE NAME |
ATYPICAL HEMOLYTIC UREMIC SYNDROME COMPLEMENT P |
| PROCEDURE MASTER NUMBER |
LAB11038 |
| SHORT PROCEDURE NAME |
ATYPICAL HEMOLYTIC UREMIC SYNDROME COMPLEMENT P |
| CATEGORY CODE |
1.0 |
| CATEGORY CODE RECORD NAME |
LAB BLOOD ORDERABLES |
| SYNONYMS |
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| CLINICALLY ACTIVE |
Yes |
| ORDERABLE |
Yes |
| PERFORMABLE |
Yes |
| FILTER GENOMICS |
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| REFERENCE LINK URL |
https://labs.northwell.edu/epic/test/114482 |
| ORDERING INSTRUCTIONS |
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| DEFAULT SPECIMEN TYPE |
Blood |
| SPECIMEN TYPE PICK LIST |
Blood |
| SPECIMEN TYPE LIST |
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| OP SPECIMEN TYPE LIST |
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| SPECIMEN SOURCE PICK LIST |
Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous |
| SPECIMEN SOURCE DEFAULT - MALE |
Blood, Venous |
| SPECIMEN SOURCE DEFAULT - FEMALE |
Blood, Venous |
| SPECIMEN SOURCE LIST |
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| OP SPECIMEN SOURCE LIST |
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| IP LAB TEST COMPONENTS FOR REPORT |
AHUSINT ALTCOMPPATH C3COMP C4COMP CBBCOMP COMTOTS FACTORB FACTORH MEDTAKEN SC5B9CO |
| OP LAB TEST COMPONENTS FOR REPORT |
AHUSINT ALTCOMPPATH C3COMP C4COMP CBBCOMP COMTOTS FACTORB FACTORH MEDTAKEN SC5B9CO |
| ORDER QUESTIONS |
["3046000027"] |
| ORDER QUESTIONS RECORD NAME |
NH IP AHUSEOR |
| INPATIENT ORDER QUESTIONS |
["3046000027"] |
| INPATIENT ORDER QUESTIONS RECORD NAME |
NH IP AHUSEOR |
| ORDER SPECIFIC QUESTION OVERRIDE |
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| INPATIENT QUESTION OVERRIDE |
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| LOCATION RESTRICT LIST IP |
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| LOCATION RESTRICT LIST IP RECORD NAME |
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| LOCATION RESTRICT LIST INCLUDE IP |
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| LOCATION RESTRICT LIST OP |
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| LOCATION RESTRICT LIST OP RECORD NAME |
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| LOCATION RESTRICT LIST INCLUDES OP |
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| EDP AMB ORDER SPECIFIC QUESTIONS RECORD NAME |
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| EDP IP ORDER SPECIFIC QUESTIONS RECORD NAME |
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| EDP IP SPECIMEN SOURCE |
Blood, Venous Blood, Central Line Blood, Arterial Blood, Capillary Blood, Peripheral |
| EDP OP SPECIMEN SOURCE |
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| EDP IP SPECIMEN TYPE |
Blood |
| EDP OP SPECIMEN TYPE |
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| DERIVED EDP IP BUTTONS S |
Blood, Capillary Blood, Arterial Blood, Central Line Blood, Venous |
| DERIVED EDP IP BUTTONS T |
Blood |
| DERIVED EDP OP BUTTONS S |
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| DERIVED EDP OP BUTTONS T |
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| IP ORDERABLE |
1 |
| OP ORDERABLE |
1 |
| STANDARD LAB COMPONENTS |
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| STANDARD LAB COMPONENTS RECORD NAME |
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| COMPONENT DATA REQUIREMENT |
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EPIC OP AOEs
| Question ID | Question Name | Question | Response Type | Response List | Require Response |
| 3046000027 |
NH IP AHUSEOR |
Is Eculizumab or Ravulizumab taken? |
Custom List |
Yes
No |
Yes |
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EPIC IP AOEs
| Question ID | Question Name | Question | Response Type | Response List | Require Response |
| 3046000027 |
NH IP AHUSEOR |
Is Eculizumab or Ravulizumab taken? |
Custom List |
Yes
No |
Yes |
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EPIC Components (results - crosswalked through Cerner)
| Component ID | Component Name | Base Name | Common Name | External Name | Cerner Result PDM |
| 3047802388.0 |
FACTOR B COMPLEMENT ANTIGEN, S |
FACTORB |
FACTOR B COMPLEMENT ANTIGEN, S |
Factor B Complement Antigen, S |
225440G |
| 3047801953.0 |
COMPLEMENT C3, S |
C3COMP |
COMPLEMENT C3, S |
Complement C3, S |
225440E |
| 3047801954.0 |
COMPLEMENT C4, S |
C4COMP |
COMPLEMENT C4, S |
Complement C4, S |
225440F |
| 3047802389.0 |
FACTOR H COMPLEMENT ANTIGEN, S |
FACTORH |
FACTOR H COMPLEMENT ANTIGEN, S |
Factor H Complement Antigen, S |
225440H |
| 3047800975.0 |
ALTERNATIVE COMPLEMENT PATH FUNC, S |
ALTCOMPPATH |
ALTERNATIVE COMPLEMENT PATH FUNC, S |
Alternative Complement Path Func, S |
225440D |
| 3047803109.0 |
IS ECULIZUMAB OR RAVULIZUMAB TAKEN? |
MEDTAKEN |
IS ECULIZUMAB OR RAVULIZUMAB TAKEN |
Is Eculizumab or Ravulizumab taken? |
225440B |
| 3047801681.0 |
CBB COMPLEMENT, P |
CBBCOMP |
CBB COMPLEMENT, P |
CBb Complement, P |
225440J |
| 3047800899.0 |
ATYPICAL HEMOLYTIC UREMIC SYNDROME INTERPRETATION |
AHUSINT |
ATYPICAL HEMOLYTIC UREMIC SYNDROME INTERPRETATION |
AHUS Interpretation |
225440A |
| 3047801956.0 |
COMPLEMENT, TOTAL, S |
COMTOTS |
COMPLEMENT, TOTAL, S |
Complement, Total, S |
225440C |
| 3047804663.0 |
SC5B-9 COMPLEMENT, P |
SC5B9CO |
SC5B 9 COMPLEMENT, P |
SC5b-9 Complement, P |
225440K |
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