NUDT15 Genotype and TPMT TPNUQ

Synonyms

Allscripts (AEHR) Order Name

NUDT15 Genotype and TPMT

Sunrise Clinical Manager (SCM) Order Name

NUDT15 Genotype and TPMT

EPIC Order Name

NUDT15 Genotype and TPMT

Clinical Info

Predicting potential for toxicity to thiopurine drugs (6-mercaptopurine, 6-thioguanine, and azathioprine)

Specimen Type

Blood

Specimen Volume

Container

Lavender Top Tube

Collection Instructions

Specimen Type: Whole blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL

Specimen Type: Cord blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL

Specimen Type: Saliva
Patient Preparation: Patient should not eat, drink, smoke, or chew gum 30 minutes prior to collection.
Supplies: Saliva Swab Collection Kit 

Specimen Type: Extracted DNA
Container/Tube:
Preferred: Screw Cap Micro Tube, 2 mL with skirted conical base
Acceptable: Matrix tube, 1 mL
Collection Instructions:
1. The preferred volume is at least 100 mcL at a concentration of 75 ng/mcL.
2. Include concentration and volume on tube.

Transport Instructions

Varies

Specimen Stability

Specimen Stability Information: 
Whole Blood and Cord Blood: Ambient (preferred) 4 days/Refrigerated 4 days/Frozen 4 days
Saliva: Ambient (preferred) 30 days/Refrigerated 30 days
Extracted DNA: Frozen (preferred) 1 year/Ambient/Refrigerated

Methodology

Real-Time Polymerase Chain Reaction (PCR) With Allelic Discrimination Analysis

Days Performed

TAT: 3 - 5 Days

Performing Laboratory

Mayo medical Labs 

CPT

OO34U
Loinc Code: 93193-1

PDM

235499

Result Interpretation

Forms