HLA Antigen B5701 zHLAB5701

Synonyms

Allscripts (AEHR) Order Name

Not Orderable

Sunrise Clinical Manager (SCM) Order Name

Not Orderable

Clinical Info

Abacavir hypersensitivity has been shown to be associated with the human leukocyte antigen (HLA) B*57:01 of the major histocompatibility complex (MHC). The MHC family of genes codes for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T cell receptors to elicit an immune response. The presence of the HLA-B*57:01 allele increases the susceptibility to abacavir hypersensitivity in several populations studied.

Specimen Type

Blood

Container

Lavender Top Tube

Collection Instructions

Container/Tube: Lavender (EDTA) top tube
Specimen: 7.0 mL whole blood (3.0 mL min)
Transport Temperature: Room Temperature

Transport Instructions

Room Temperature

Specimen Stability

Methodology

Polymerase chain reaction (PCR)/sequence-specific oligonucleotide probes (SSOP)
 
This is a class I allele-specific test.

Days Performed

Performing Laboratory

LabCorp of America

CPT

81381

PDM

5902530

Result Interpretation

See Report
 
TAT: 6 - 8 Days

Forms


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