Homovanillic Acid(HVA), Random Urine HVARU

Synonyms

Allscripts (AEHR) Order Name

Homovanillic Acid (HVA), Random Urine

Sunrise Clinical Manager (SCM) Order Name

Homovanillic Acid (HVA), Random Urine

EPIC Order Name

Random Urine, Homovanillic Acid (HVA)

Clinical Info

Homovanillic acid (HVA) and other catecholamine metabolites (vanillylmandelic acid: VMA and dopamine) are typically elevated in patients with catecholamine-secreting tumors (eg, neuroblastoma, pheochromocytoma, and other neural crest tumors). HVA and VMA levels may also be useful in monitoring patients who have been treated as a result of the above-mentioned tumors.

Specimen Type

Urine

Container

Urine Cntr

Collection Instructions

Container/Tube: Plastic Urine Container or Tube with No Preservative
Specimen: 5 mL Random Urine ( 2 mL min)
Transport Temperature: Refrigerated
Stability; 28 Days Refrigerated
180 Days Frozen
Patient Preparation: Administration of L-dopa may falsely increase homovanillic acid results; it should be discontinued 24 hours prior to and during collection of specimen.

(Lab Use only- Adjust the urine pH to a level between 1 and 5 by adding 50% acetic acid dropwise and checking the pH.)

Transport Instructions

Refrigerated

Specimen Stability

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Days Performed

TAT: 3-5 Days

Performing Laboratory

Mayo Medical Laboratories

CPT

83150

PDM

2114159

Result Interpretation

Reference Ranges
<1 year:	<35.0	mg/g	creatinine
1 year:	<30.0	mg/g	creatinine
2-4 years:	<25.0	mg/g	creatinine
5-9 years:	<15.0	mg/g	creatinine
10-14 years:	<9.0	mg/g	creatinine
> or =15 years (adults):	<8.0	mg/g	creatinine

Forms